Zollinger-Ellison syndrome Flashcards
1
Q
What is the typical characteristic of Zollinger-Ellison syndrome
A
excessive levels of gastrin, (usually from a gastrin secreting tumour)
2
Q
Where is a gastrin-secreting tumour usually found in Zollinger-Ellison syndrome?
A
duodenum or pancreas
3
Q
What condition is associated with Zollinger-Ellison?
A
MEN type I syndrome (30% tumours arise due to this)
4
Q
Features of ZE
A
multiple gastroduodenal ulcers
diarrhoea
malabsorption
5
Q
What investigations can be diagnostic of ZE?
A
- fasting gastrin levels (gold standard)
- secretin stimulation test
6
Q
A
