NAFLD Flashcards
1
Q
Describe the different stages of NAFLD
A
steatosis - fat in the liver
steatohepatitis - fat with inflammation
progressive disease may cause fibrosis and liver cirrhosis
2
Q
Conditions associated with NAFLD
A
- obesity
- type 2 diabetes mellitus
- hyperlipidaemia
- jejunoileal bypass
3
Q
Clinical features of NAFLD
A
- asymptomatic
- hepatomegaly
- ALT > AST
- increased echogenicity on ultrasound
4
Q
What blood test is recommended by NICE to screen for advanced liver fibrosis in NALFD patients
A
enhanced liver fibrosis (ELF) blood test
hyaluronic acid + procollagen III + tissue inhibitor of metalloproteinase 1
5
Q
What other investigations can predict the likelihood of fibrosis in NAFLD?
A
Calculating a FIB4 score or NALFD fibrosis score
these scores may be used in combination with a FibroScan (liver stiffness)
6
Q
Management of NAFLD
A
- weight loss/lifestyle change
7
Q
A
