IBD Flashcards
Bloody diarrhoea more common
Abdominal pain in the left lower quadrant
Tenesmus
Ulcerative Colitis
Diarrhoea usually non-bloody
Weight loss more prominent
Upper gastrointestinal symptoms, mouth ulcers, perianal disease
Abdominal mass palpable in the right iliac fossa
Crohns
Primary sclerosing cholangitis more commonly associated with this IBD
UC
Gallstones are more common in this IBD secondary to reduced bile acid reabsorption
Crohns
Complications include:
Bowel obstruction, fistula, colorectal cancer
Crohns
Colorectal cancer risk is higher in this IBD
UC
Lesions may be seen anywhere from the mouth to anus
Skip lesions may be present
Crohns
Inflammation always starts at rectum and never spreads beyond ileocaecal valve
Continuous disease
UC
Histology shows:
- inflammation in all layers from mucosa to serosa
- increased goblet cells
- granulomas
Crohns
Histology shows:
- No inflammation beyond submucosa
- inflammatory cell infiltrate in lamina propria
- crypt abscesses
- depletion of goblet cells
- infrequent granulomas
UC
Endoscopy appearance:
Deep ulcers
skip lesions - ‘cobble-stone’ appearance
Crohns
Endoscopy appearance:
Widespread ulceration
psuedopolyps
UC
Radiology findings:
- strictures: ‘Kantor’s string sign’
- proximal bowel dilation
- ‘rose thorn’ ulcers
- fistulae
Crohns
Radiological Findings:
- Barium enema
- loss of haustrations
- superficial ulceration
- ‘pseudopolyps’
- ‘drainpipe colon’ in chronic disease
UC