XXVI - Anti-Parkinsonism Drugs

Question 1

DOC for Parkinson’s disease

Answer 1

Levodopa + Carbidopa

Question 2

Why should you co-administer Carbidopa with Levodopa?

Answer 2

to inhibit peripheral metabolism of Levodopa

Question 3

Anti-Parkinsonism drug used to treat hyperprolactinemia, SE: erythromelalgia (extremity swelling), pulmonary fibrosis

Answer 3

Bromocriptine

Question 4

Adjunctive drug for the wearing-off phenomena in Parkinson’s

Answer 4

Entacapone

Question 5

Anti-Parkinsonism drug with antiviral properties, SE: livedo reticularis, cerebellar ataxia

Answer 5

Amantadine

Question 6

Improves tremor and rigidity but has no effect on bradykinesia, has atropine-like effects

Answer 6

Benztropine

Question 7

Anti-Parkinsonism drugs that have atropine-like effects

Answer 7

Trihexyphenidyl, Benztropine, Biperiden

Question 8

Primary signs of Parkinson’s

Answer 8

Tremor, Rigidity, Akinesia, Postural Instability

Question 9

Drugs that can cause livedo reticularis

Answer 9

Amantadine, Hydroxyurea, Minocycline, Gemcitabine, Quinidine