XXII - Sedative Hypnotics

Question 1

Acute anxiety attacks, anesthesia induction, preoperative sedation

Answer 1

Midazolam

Question 2

Seizure disorders (status epilepticus), alcohol withdrawal, tranquilizer

Answer 2

Diazepam

Question 3

Date-Rape Drugs

Answer 3

Alcohol, Flunitrazepam (Rohypnol), Gamma-hydroxybutyrate

Question 4

Antidote to benzodiazepine overdose

Answer 4

Flumazenil

Question 5

Anesthesia induction, lethal injection, truth serum

Answer 5

Thiopental

Question 6

Seizure disorders in children, SE: precipitates porphyria, CYP450 inducer

Answer 6

Phenobarbital

Question 7

Cl-Channel Effects: Benzodiazepines

Answer 7

↑ frequency

Question 8

Cl-Channel Effects: Barbiturates

Answer 8

↑ duration

Question 9

Abnormal sleep pattern from benzodiazepines

Answer 9

↓ REM sleep

Question 10

Benzodiazepine with the longest half-life

Answer 10

Chlordiazepoxide

Question 11

Barbiturate with the shortest half-life

Answer 11

Thiopental

Question 12

Most catastrophic symptom of sedative-hypnotic withdrawal

Answer 12

rebound suicide

Question 13

Sleep disorders

Answer 13

Zolpidem, Zaleplon

Question 14

Generalized anxiety disorders, onset of 2 weeks, acts like a benzodiazepine

Answer 14

Buspirone

Question 15

Sedative-Hypnotic Poisoning

Answer 15

Hypothermia, Hypotension, Hypoactive BS, Disinhibition, Coma, Nystagmus