XI- Anti-Cholesterol Agents Flashcards
1
Q
HMG-CoA reductase inhibitor, lowers LDL, SE: hepatotoxicity, rhabdomyolysis, myopathy
A
Simvastatin
2
Q
Bile acid binding resin, lowers LDL, SE: constipation, steatorrhea, contraindicated in hyperTG
A
Cholestyramine
3
Q
Cholesterol absorption blocker, lowers LDL
A
Ezetimide
4
Q
Reduces all building blocks for hyperlipidemia, increases HDL, lowers LDL and TG, SE: flushing, hyperglycemia, hyperuricemia
A
Niacin
5
Q
PPAR-α activator, upregulates lipoprotein lipase, lowers TG, SE: gallstones, additive myopathy
A
Gemfibrozil (Fibrate)
6
Q
Use of statins in coronary artery disease
A
stabilize the plaque
7
Q
Drugs that cause flushing
A
Vancomycin, Adenosine, Niacin,CCBs
