Xanthogranulomatous pyelonephritis Flashcards

1
Q

What is xanthogranulomatous pyelonephritis?

A

Rare form of chronic pyelonephritis and represents a chronic granulomatous disease resulting in a non-functioning kidney

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2
Q

What causes xanthogranulomatous pyelonephritis?

A

Chronic granulomatous process believed to be the result of subacute/chronic infection inciting a chronic but incomplete immune reaction

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3
Q

How does xanthogranulomatous pyelonephritis present?

A
  • Typically vague, consisting of constitutional symptoms such as malaise, weight loss and low-grade fever
  • Haematuria and flank pain are sometimes encountered
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4
Q

What are some investigations required in xanthogranulomatous pyelonephritis?

A

Imaging - x-ray, USS, CT (most useful), MRI

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5
Q

How is xanthogranulomatous pyelonephritis managed?

A

Surgical nephrectomy is usually curative

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