Priapism Flashcards
What is priapism?
Prolonged unwanted erection (> 4 hours), often painful and not associated with sexual arousal
What are some causes of priapism?
- Intracorporeal injection for ED e.g. papavarine
- Trauma (penile/perineal)
- Haematological dyscrasias e.g. sickle cell
- Neurological conditions
- Idiopathic
What are the 2 pathophysiological mechanisms of priapism?
Ischaemic (Veno-oclusive or low-flow)
Non-ischaemic - Less urgent
Describe the pathophysiology of ischaemic priapism
- Vascular stasis in penis and decreased venous outlfow - a true compartment syndrome
- Corposa cavernosa are rigit and tender, penis often painful
Describe the pathophysiology of non-ischaemic priapism?
- Traumatic distuption of penile vasculature results in unregulated blood entry and filling of corpora
- Fistula formation betweenc cavernous artrery and lacinar spaces allows blood to bypass the normal helicine arteriolar bed
What investigations are required in priapism?
Aspirate blood from corpus cavernosum
Colour duplex USS
What will be seen on blood aspiration from the corpus cavernosum in priapism?
- Dark blood, low O2 and high CO2 in low-flow
- Normal arterial blood in high-flow
What will be seen on colour duplex USS in priapism?
- Minimal or absent flow in cavernosal arteries in low-flow
- Normal to high flow in non-ischaemic priapism
How is ischaemic priapism managed?
- Aspiration +/- irrigation with saline
- If fails to resolve - injection of ⍺-agonist e.g. phenylephrine
- If fails to resolve - surgical shunt
How is delayed presentation of priapism managed?
- Ischaemic priapism > 48-72 hours unlikely to respond to intracavernosal treatment
- For very delayed presentation, may even consider immediate placement of a penile prosthesis
How is non-ischaemic priapism managed?
- Observe, may resolve spontaneously
- Selective arterial embolization with non-permanent materials