Priapism Flashcards

1
Q

What is priapism?

A

Prolonged unwanted erection (> 4 hours), often painful and not associated with sexual arousal

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2
Q

What are some causes of priapism?

A
  • Intracorporeal injection for ED e.g. papavarine
  • Trauma (penile/perineal)
  • Haematological dyscrasias e.g. sickle cell
  • Neurological conditions
  • Idiopathic
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3
Q

What are the 2 pathophysiological mechanisms of priapism?

A

Ischaemic (Veno-oclusive or low-flow)
Non-ischaemic - Less urgent

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4
Q

Describe the pathophysiology of ischaemic priapism

A
  • Vascular stasis in penis and decreased venous outlfow - a true compartment syndrome
  • Corposa cavernosa are rigit and tender, penis often painful
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5
Q

Describe the pathophysiology of non-ischaemic priapism?

A
  • Traumatic distuption of penile vasculature results in unregulated blood entry and filling of corpora
  • Fistula formation betweenc cavernous artrery and lacinar spaces allows blood to bypass the normal helicine arteriolar bed
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6
Q

What investigations are required in priapism?

A

Aspirate blood from corpus cavernosum
Colour duplex USS

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7
Q

What will be seen on blood aspiration from the corpus cavernosum in priapism?

A
  • Dark blood, low O2 and high CO2 in low-flow
  • Normal arterial blood in high-flow
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8
Q

What will be seen on colour duplex USS in priapism?

A
  • Minimal or absent flow in cavernosal arteries in low-flow
  • Normal to high flow in non-ischaemic priapism
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9
Q

How is ischaemic priapism managed?

A
  • Aspiration +/- irrigation with saline
  • If fails to resolve - injection of ⍺-agonist e.g. phenylephrine
  • If fails to resolve - surgical shunt
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10
Q

How is delayed presentation of priapism managed?

A
  • Ischaemic priapism > 48-72 hours unlikely to respond to intracavernosal treatment
  • For very delayed presentation, may even consider immediate placement of a penile prosthesis
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11
Q

How is non-ischaemic priapism managed?

A
  • Observe, may resolve spontaneously
  • Selective arterial embolization with non-permanent materials
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12
Q
A
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