Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Anatomy & Physiology > Wound Healing > Flashcards

Wound Healing Flashcards

1
Q

What systemic factors positively affect wound healing?

A

Good nutritional status

Good general health

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What systemic factors negatively affect wound healing?

A

Infection
Impaired immunity
Poor blood supply
Systemic conditions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What local factors positively affect wound healing?

A

Good blood supply

Freedom from contamination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What local factors negatively affect wound healing?

A

Presence of microbes
Presence of foreign bodies
Presence of toxic chemicals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the two categories of wounds?

A

Superficial (non-bleeding)

Deep (bleeding)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is primary wound healing?

A

Closure - common following surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is a secondary wound healing?

A

Wound edges are distant from each other

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the three stages of wound healing in the order they occur?

A

Inflammatory stage
Proliferative stage
Remodelling stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is Haemostasis and at which stage of healing does it occur?

A

Body tries to stop the blood from flowing and occurs in the inflammatory stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What substance causes the blood vessels to narrow as part of haemostasis?

A

5-Hydroxytryptamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the 3 stages of the inflammatory response

A

Haemostasis
Platelet activation
Blood coagulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What type of homeostatic control mechanism is Platelet activation an example of?

A

Positive Feedback loop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What substance is produced when platelets clump as part of the platelet activation stage of the inflammatory response?

A

ADP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

As well as platelets what other substance is involved in forming a plug during the platelet activation stage?

A

Sub endothelial collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What action does thrombin carry out as part of coagulation?

A

It converts inactive fibrinogen into fibrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What function does fibrin perform in coagulation?

A

It stabilises the clot (3 dimensional meshwork)

17
Q

What are chemo attractants?

A

Growth factors released by platelets to attract Neutrophils and Macrophages to the site of a wound

18
Q

What is diapedesis and why does it occur during the inflammatory response?

A

The passage of blood cells through intact capillary walls. It occurs so that WBCs attracted by Growth factor can leak into the wound and attempt to kill any bacteria present

19
Q

Approximately how long after tissue injury do macrophages reach the site of the wound?

A

24 hours

20
Q

What do macrophages entering a wound site release and how does this help healing?

A

Growth factors which initiate the formation of granulation tissue and angiogenesis

21
Q

What is angiogenesis?

A

The formation of new blood vessels

22
Q

At what stage of wound healing does angiogenesis occur?

A

Inflammatory stage

23
Q

What role do fibroblasts have in the wound healing process?

A

They produce collagen fibres and may also have a role in angiogenesis

24
Q

What are the four types of exudate?

A

Serous
Fibrinous
Haemorrhagic
Purulent

25
Q

Why do keratinocytes release proteases during the proliferative stage of wound healing?

A

To prevent over granulation of the wound. They debride the wound

26
Q

What happens in the remodelling phase?

A

Wound closes
Cells undergo apoptosis
Tissue continuously remodelled
Scarring can occur

27
Q

Is scar tissue as strong as non-wounded tissue?

A

No, it is only 80% as strong

28
Q

What are three types of problems affecting wound healing that lead to chronic wound?

A

Ischaemia
Bacterial colonisation
Impaired neo-angiogenesis

29
Q

If there are lots of inflammatory cytokines at the site of a wound will this positively affect healing?

A

No too many will lead to an exaggerated inflammatory response and delay healing

30
Q

If there are lots of proteases released during the proliferative stage will this lead to a delay in wound healing?

A

Yes, they will prevent the wound from healing

31
Q

If there is insufficient oxygen to the wound, will this promote or delay healing?

A

Delay healing

32
Q

If there are insufficient growth factors released by platelets and macrophages will this promote or delay healing?

A

Delay healing

Anatomy & Physiology (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions