Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology Exam I > Wound Healing > Flashcards

Wound Healing Flashcards

1
Q

Wound Healing

A

restoration of tissue architecture and function after an injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Healing

A

regeneration - so restoration of both anatomy and physiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Repair

A

anatomy doesn’t get repaired, instead you have a functional compromise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Labile cells

A

normally continous turnover - have stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

stable cells

A

normally have little proliferation, but have the capability, have stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

permanent cells

A

no stem cells. heal by scarring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

2 processes of regeneration

A

proliferation of surviving cells to replace lost tissue

migration of surviving cells into the vacant space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

examples of stable cells

A

liver, kidney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

examples of permanent cells

A

brain, heart, skeletal muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

examples of labile cells

A

bone marrow, epidermis, GI and bronchial epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

When do you get partial regeneration and scaring

A

have a tissue capable of regeneration and extensive injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the 3 phases of wound healing

A
  • inflammation
  • proliferation
  • maturation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

when does inflammation normally take place

A

1st week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what happens in inflammation

A

clot formation

chemotaxis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

when does proliferation happen

A

2nd week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What happens in proliferation

A

re-epitheliazation
angiogenesis and granulation tissue
provisional matrix

17
Q

when does matruation happen

A

3rd week

18
Q

what happens in maturation

A

collagen matrix

wound contraction

19
Q

What is angiogensis

A

capillary budding

endothelial cell proliferation

20
Q

what is the major regulatory molecule of angiogensis

A

VEGF

21
Q

what is fibrogenesis

A

fibroblast activation and proliferation, collagen deposition

22
Q

what is the major stimulatory molecule of fibrogenesis

A

TGF-beta

23
Q

what is the director of wound healing

A

macrophage

24
Q

when does granulation tissue show up

A

proliferation

25
Q

what does granulation tissue look like grossly

A

pink, soft, granular, seen beneath the scab of a skin wound

26
Q

what does granulation tissue look like histology

A

fibroblasts surrounded by abundant ECM, newly formed blood vessels and scattered macrophages and some other inflammatory cells

27
Q

what does early granulation tissue look like

A

numerous macrophages, myofibroblasts and blood vessels

28
Q

what does late granulation tissue look like

A

less vascular, only scattered macrophages with more matrix and fibroblasts

29
Q

Granulation is a ___ structure

A

temporary

30
Q

what can contraction lead to

A

considerable deformity and functional impairment

31
Q

the more granulation the ____ contraction and ____ risk of organ impairment

A

more

greater

Pathology Exam I (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions