wk 7: blood, lymph, and immune system Flashcards
functions of blood
- maintains body’s homeostasis
- transport nutrients, vitamins, and minerals
- transports waste products
- transports hormones
- transports gases
- protect against foreign substances
- forms clots
white blood cells can be categorized into…
granulocytes or agranulocytes
leuk/o-
R/CF: white
erythr/o-
R/CF: red
fibr/o-
R/CF: fiber
-blast
S: immature cell
-stasis
S: control, stop
hem/o-
R/CF: blood
thromb/o-
R/CF: blood clot
antigens
a substance capable of triggering an immune response
*loc: surface of RBCs
loc: antibodies
in the plasma
antigens can be categorized into what two groups?
ABO and Rh
a person with only antigen A has…
type A blood
a person with only antigen B has…
type B blood
a person with both antigen A and antigen B has…
type AB blood
a person with neither antigen has…
type O blood
which blood type is known as the universal donor?
type O blood
if an Rh antigen is present, the blood is said to be…
Rh-positive
anti-
P: against
-gen
R: produce, create
-body
R: substance, body
Rhesus factor
Greek: mythical king of Thrace
what are the body’s three lines of defense?
- physical
- humoral
- cellular
physical defense mechanism examples?
- skin
- hair
- mucous membranes
- saliva, sweat, & tears
- cilia & mucus
humoral defense mechanism examples?
antibodies
- tag bacteria, etc for destruction
cellular defense mechanism examples?
lymphocytes
- directly attack suspicious cells
what are the functions of the lymphatic system?
- absorbs excess interstitial fluid & return it to the bloodstream
- remove foreign chemicals, cells, and debris from tissues
- absorb dietary lipids from the small intestine
T lymphocytes
“T” for thymus: location of where these cells develop and mature
- 75% - 85% of body lymphocytes
B lymphocytes
- mature in bone marrow
- 15-25% of lymphocytes
- become plasma cells to produce antibodies
what is the largest lymphatic organ? where is it located?
the spleen
*loc: LUQ of abdomen; below the diaphragm and lateral to the kidney
what are the functions of the spleen?
- phagocytose (consume) foreign material
- phagocytose old RBCs and platelets
- initiate an immune response
- serve as a reservoir for RBCs and platelets
the thymus is Greek for…
sweetbread
how does immunity differ from the physical and cellular mechanisms?
- specificity: directed against a specific pathogen
- memory: can recognize a previous pathogen and is prepared to act against it
- discrimination: learns to recognize “self” b/w “nonself” (foreign)
what is immunity?
the ability to resist a specific infectious diseases
cellular (cell-mediated) immunity
-a direct form of defense
- attack and destroy foreign and diseased cells
humoral (anttibody-mediated) immunity
- an indirect form of definition
- employs antibodies produced by plasma cells (tag to destroy)
-lysis
S: destruction
-lyt-
R: destroy
per-
P: through
ag- (ad-)
P: to
-glutin-
R: stick
palor
Latin: paleness
-nici-
R: lethal
a normal cubic mm of blood contains _____ WBCs
5,000 to 10,000
in leukocytosis, the total WBC count exceeds…
101,000 per cubic mm
what conditions can increase the WBC count beyond its normal range?
- allergic reactions (+ # of eosinophils)
- typhoid fever, maleria, TB (+ # of monocytes)
- bacterial infections (+ # of lymphocytes)
leukemia
- cancer of blood forming tissues
- leukemic cells multiply and take over the bone marrow causing a deficiency in RBCs, WBCs, and platelets
leokopenia
WBC count drops below 5,000 cells per cubic mm
pancytopenia
noteably reduced RBCs, WBCs, and platelets.
hypersensitivity includes:
- allergies
- autoimmune disorders
- alloimmune disorders
allergies
reaction to environmnetal antigens
autoimmune disorders
abnormal reactions to your own tissues
alloimmune disorders
reactions to tissues transplanted from another person
what three categories can immunodeficiency be classified into?
- congenital (inborn) disorders
- immunosuppression
- acquired immunodeficiency
HIV
AIDS
coagul/o-
R/CF: clotting
occult
Latin: to hide
par-
P: abnormal
-enter-
R: intestine
Hct
hematocrit
Ig
immunoglobin
DIFF
differential
EBV
epstein-Barr virus (kissing diseases/infectious mononucleosis)
PMNLs
polymorphonuclear leukocytes/neutrophils
hemostasis
control of bleeding
agglutin/o-
R/CF: clumping
granul/o-
R/CF: granules
hem/o
R/CF: blood
phag/o-
R/CF: eat. swallow