Why can't you remember this stuff. Flashcards

1
Q

IgG, IgM, C3 GM deposits, “lumpy bump”, “starry sky”

A

acute post strep gnp

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2
Q

linear deposits on glomerular IF

A

goodpastures, RPGN

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3
Q

“spike and dome” on glomerular em

A

membranous nephropathy

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4
Q

eosinophilic pyruria

A

acute interstitial nephritis

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5
Q

“muddy brown” casts in urine

A

ATN

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6
Q

statins

A

lower LDL

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7
Q

ezetimibe

A

lower LDL

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8
Q

bile acid sequestrants

A

lower LDL

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9
Q

niacin

A

increases HDL

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10
Q

fibrates

A

lower TGs

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11
Q

Li treats…

A

BIPOLAR DISORDER

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12
Q

tx of Cu overload (wilson)

A

penicillamine

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13
Q

tx of panic disorder

A

attack: benzo, LT: SSRI/SNRI

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14
Q

MOA phenytoin

A

blocks Na channels

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15
Q

MOA carbamazepine

A

blocka NA channels

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16
Q

MOA valproate

A

increase Na channel inactivaion, blocks T-type ca channels

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17
Q

MOA lamotrigine

A

block v-gates Na channels

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18
Q

SAE lamotrigine

A

SJS

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19
Q

MOA gabapentin

A

inhibits presynaptic v-gated Ca channels

20
Q

MOA ethosuximise

A

blocks thalamic T-type ca channels

21
Q

senile plaques

A

extracellular beta-amyloid deposits seen in alzheimers

22
Q

NF tangles

A

made of hyperP tau protein seen in alzheimers

23
Q

lewy bodies are made of

A

alpha-synuclein

24
Q

pick bodies are made of

A

hyperP tau protein

25
Q

drug that targets inactive Na channels (ischemic areas post MI)

A

class IB antiarrythmics > lidocaine, mexiletine

26
Q

antiSm Ab is aka

A

spliceosomal snRNP ab

27
Q

AE: aminoglycosides (-mycin)

A

Nephrotox, ototox (esp with loops), NMJ block (CI in MG)

28
Q

AE: tetracyclines

A

teeth discoloration, photosensitivity

29
Q

AE: chloramphenicol

A

gray baby syndrome

30
Q

AE: clindamycin

A

pseudomembranous colitis

31
Q

AE: linezolid

A

5HT syndrome, BM suppression

32
Q

AE: macrolides

A

QT prolongation, GI motility issues, CYP-450 inh

33
Q

blood solubility indicates a drug’s

A

induction and recovery time (inverse relationship)

34
Q

lipid solubility indicates a drug’s

A

potency (direct correlation)

35
Q

MAC is

A

inversely proportional to potency

36
Q

N2O: solubility, induction, potency

A

low blood and lipid sol, fast induction, low potency

37
Q

collects data from a group of ppl to assess fx of dz at a point in time

A

cross-fxnl study

38
Q

compares a group of people with disease to a group of ppl without disease

A

case-control study (use OR)

39
Q

compares a group with a given exposure or risk factor to a group without such exposure - did the expose affect the likelihood of dz?

A

cohort study (use RR)

40
Q

afferent and efferent limb of pupillary light reflex

A

aff> CN II, eff>CN III

41
Q

ACEi decrease GFR via

A

preventing the constriction of the efferent arteriole

42
Q

secretes PTHrP

A

sq cell lung ca!

43
Q

columnar tumor cells growing along alveolar walls

A

bronchoalveolar lung cancer

44
Q

MC lung cancer in non smokers

A

adenocarcinoma

45
Q

antibody of MCTD

A

anti-RNP Ab

46
Q

von girke is a mutation in

A

glucose-6-phosphatase > get hepatomegaly