Drug Endings

Question 1

-dronate, ex: resindronate

Answer 1

bisphosphonates - used to prevention and tx of osteoporosis, CI = pre-existing hypocalcemia

Question 2

-dine

Answer 2

H2 blocker - used to tx peptic ulcers

Question 3

-prazole

Answer 3

PPI

Question 4

-chol

Answer 4

Cholinomimetics - direct agonists

Question 5

-stigmine

Answer 5

AChE inhibitors

Question 6

-trope, -scope

Answer 6

mAChR antagonists

Question 7

-osin

Answer 7

Alpha1 selective blocker

Question 8

-zolamide

Answer 8

Carbonic anhydrase inhibitor

Question 9

-pril

Answer 9

ACEi

Question 10

-sartan

Answer 10

Angiotensin II inhibitors

Question 11

-dipine

Answer 11

ca ch blocker that acts at the level of the blood v

Question 12

-afil

Answer 12

PDE5 inhibitors

Question 13

-statin

Answer 13

HMG-CoA reductive inhibitors

Question 14

-ane

Answer 14

Inhaled anesthetic

Question 15

-curium, -curonium

Answer 15

Nondepol NM blocking drugs

Question 16

-mycin

Answer 16

Macrolide abx - inh 50s ribosome

Question 17

-floxacin

Answer 17

Fluroquinolones - inh topoisomerase II (DNA gyrase) and IV, good for GM -

Question 18

-navir

Answer 18

Protease inhibitor - prevents maturation of new viruses (HIV tx)

Question 19

-tegr-

Answer 19

Integrase inh - stops HIV genome from integrating into host genome (HIV)

Question 20

-grel

Answer 20

ADP receptor inh - inh platelet aggregation (reversible)

Question 21

-glitazone

Answer 21

Thiazolidinediones - increase insulin sensitivity by binding to PPAR-gamma (DM T2)

Question 22

-gliptin

Answer 22

DDP-4 inh - work synergistically with GLP-1 analogues to increase actor form (DM T2)

Question 23

-gliflozin

Answer 23

sGLT-2 inh - block reabs of glucose

Question 24

-azine

Answer 24

typical antipsychotics (neuroleptics) > block D2 receptors