WHO 2017 MALIGNANT

Question 1

List Malignant odontogenic tumors based on 2017 WHO classification

Answer 1

AC (Ameloblastic Ca)
PIOC (Primary intraosseous Ca - NOS)
SOC (Sclerosing odontogenic Ca)
CCOC (clear cell odontogenic Ca)
GCOC (ghost cell odontogenic Ca)
OCS (odontogenic carcinosarcoma)
OS (odontogenic sarcoma)

Question 2

Ameloblastic carcinoma types

Answer 2

No types in 2017.
All types being in a single entity now.
Previous types categorized into primary, secondary intraosseous, secondary peripheral.

Question 3

PIOC as a single entity in 2017. True or Falso.

Answer 3

True. Regardless of precursor of the malignancy (ie radicular/residual/dentigerous/okc),
they are all now considered PIOC.

Question 4

Diff dx of PIOC

Answer 4

All malignant odontogenic tumors:
- Ameloblastic Ca
- SOC
- CCOC
-CGOC
Intraosseous mucoepidermoid Ca
Metastatic lesion

Question 5

Sclerosing odontogenic carcinoma

Answer 5

New odontogenic ca

characterized by small single-file cords and strands of epithelium.

Question 6

Diff diagnosis of SOC

Answer 6

Central odontogenic fibroma
Desmoplastic ameloblastoma
CEOT
CCOC
Mets

Question 7

Diff dx of CCOC

Answer 7

Metastatic renal cell carcinomas
Melanoma
Intraosseous MEC

Question 8

GCOC

Answer 8

Malignant counterpart of calcifying odontogenic cyst

Question 9

Odontogenic carcinosarcoma types

Answer 9

Has 3 types

• ameloblastic fibrosarcoma (MOST COMMON)
• ameloblastic fibrodentinosarcoma
• ameloblastic fibroodontosarcoma