WHO 2017 BENIGN tumors

Question 1

Benign EPITHELIAL tumors of odontogenic origin based on 2017 WHO classification

Answer 1

Ameloblastoma, conventional
Ameloblastoma, unilocular
Ameloblastoma, extraosseous/peripheral
Metastasizing (malignant) ameloblastoma
Squamous odontogenic tumor
Calcifying epithelial odontogenic tumor
Adenomatoid odontogenic tumor

Question 2

Histopathological types of ameloblastoma

Answer 2

Follicular (most common & most diagnostic)
Plexiform
Basaloid
Granular
Acanthomatous
Desmoplastic

Question 3

Subtypes of unicystic ameloblastoma

Answer 3

Luminal - only cyst lining is affected
Intraluminal - solid neoplasm grown intraluminally
Mural - neoplasm infiltrated the wall

Question 4

Recurrence rate of Unicystic ameloblastoma

Answer 4

3-4% for resection
30% for enucleation alone
16-20% for enucleation followed by application of Carnoy’s solution
18-20% for marsupialization with/without second phase tx

Question 5

Diagnosing ameloblastoma

Answer 5

1. Clinical
   Bony expansion buccolingually
   Facial disfigurement
   Mobile teeth
2. Radiographical
   Multilocular radiolucency (honeycomb/soap-bubble appearance) *except Desmoplastic - more radiopaque dt collagenized stroma
   Posterior mandible
   Root resorption or displacement
3. Histopathological
   Palisaded ameloblast cells - tall columnar/cuboidal cells
   Reverse polarization

Question 6

Treatment of ameloblastoma, conventional

Answer 6

Resection

Question 7

Treatment of extraosseous, peripheral ameloblastoma

Answer 7

1.

Question 8

Treatment of unicystic ameloblastoma

Answer 8

enucleation with carnoys solution

Question 9

recurrence rate for ameloblastoma

Answer 9

resection 0-3%
marginal resection 10-15%
conservative (enucleation, curretage, marsupialization) 60-80%

Question 10

AOT pathogenesis

Answer 10

Remnant of Hertwigs epithelial root sheath

Question 11

How does AOT clinically present

Answer 11

Pear shaped radiolucency around an impacted tooth that extends beyond the CEJ of tooth

Question 12

AOT as a disease of 3

Answer 12

2/3 occurs in young females, anterior maxilla, impacted canine

Question 13

Diagnostic character of CEOT

Answer 13

Mixed radiolucent radiopaque lesion - on Radiograph

Contains extracellular amyloid protein that calcifies - histopath

Question 14

Benign MIXED tumors of odontogenic origin based on 2017 WHO classification

Answer 14

ameloblastic fibroma
primordial odontogenic tumor
odontoma - complex and compound
DGOT

Question 15

Benign MESENCHYMAL tumors of odontogenic origin based on 2017 WHO classification

Answer 15

Odontogenic fibroma
Odontogenic myxoma
Cementoblastoma
Cementoossifying fibroma

Question 16

Diagnostic character of CEOT

Answer 16

Radiographic - mixed lucency and opacity

Histopath - contains extracellular amyloid protein that calcifies

Question 17

Dentigerous ghost cell tumor diff diagnosis

Answer 17

Ameloblastoma

Question 18

Diagnostic feature of DGOC

Answer 18

Histopath similar with ameloblastoma but contains ghost cells >2%%
Presence of dentinoid
Its a neoplasm form of Calcifying odontogenic cyst

Question 19

What tumors are associated wth mutation in the PTCH gene

Answer 19

OKCs - gorlin goltz syndrome
CEOT
Odontogenic myxoma
*but these 2 not associates with gorlin goltz