Salivary Gland Disease Flashcards
Investigations in salivary gland dz
Plain films - detect stone/foreign body
USG - detect mass or stone
CT/MRI - to assess extend size location of mass; mri allows neural involvment assessment
Sialogram - using contrast agent injected into ductal system to see its morphology and anatomy for any obstruction, strictures, sialectasia
Core needle biopsy - ct/usg guided to give definite histopath dx
Sialendoscopy - diagnostic / therapeutic
Scintigraphy - assessment of function of parenchyma using radioisotope technetium 99
Causes of xerostomia
Inflammatory - infection hep b,c, HIV, GVHD
Neoplasia - benign or malignant
Drugs - antihpt, tca antidepressant, narcotics, benzodiazepines, anticholinergic, beta blockers, antihistamines, diuretics
Iatrogenic - local factors - smoking, mouth breathing
Congenital - aplasia
Autoimmune - sjogrens, sarcoidosis, amyloidosis
Trauma - obstructive
Endocrine - DM, DI
Whats the sequalae of xerostomia?
Sialedenitis
Sialolithiasis
Presentation of sialadenitis
Pain at the affected salivary gland on eating Swelling Erythematous Fever Purulent discharge
Imaging required for sialadenitis
Plain radiograph - opg, occlusal to rule out sialolithiasis
Sialography - to assess the ductal system and see sialectasis proximal to any obstruction
Chronic sialadenitis will show sausaging - due to scarring and stricture of ductal system.
Ct/mri - to rule out neoplasm
Diff dx of sialadenitis
Sialolithiasis
Salivary gland neoplasia
Investigations of sialadenitis
- Imaging
- C&S if pus present
- Bloods (cbc - increase neutrophils, raised esr)
Initial management of sialadenitis
Hydration Antibiotics Analgesias Steroids Sialogogues I&d if abscess present Glandular massage
If unresolved with initial therapy, whats the next tx?
Minimally invasive
- sialendoscope with ductal irrigation +/- ductal stenting if stricture is present
Invasive (if still recur, persist, with destruction of gland parenchyma)
- surgical removal of gland
When do you do removal of salivary gland? whats the indication?
Sialolithiasis ( 3 conditions)
- stone severely impacted at hilar region of submandibular gland
- intraparenchymal calculi
- calculi beyond the muscles (mylohyoid for submandibular, masseter for parotid)
Salivary neoplasm
Recurrent persistent sialadenitis
Whats the presentation of obstructive salivary gland dz
Mealtime syndrome
What is mealtime syndrome
A collection of symptoms occurring due to increase salivary flow during or when meal is anticipated, but unable to be secreted due to obstruction, leading to gland capsule distension and swelling.
How does mealtime syndrome presents with
Acute recurrent pain and swelling during or when meal is anticipated, and subsides after meal.
Where does stone commonly occur in submandibular gland?
- At hilar region of submandibular gland where it wraps around the mylohyoid muscle
- Intraparenchymal
- Terminal end of the duct
Why is submandibular gland most common to have sialolithiasis
- Long tortous submandibular duct
- Antigravity flow of the submandibular gland saliva
- Mucinous saliva