White Lesions Flashcards
Most common oral precancerous lesion
Leukoplakia
Leukoplakia most commonly found on
Lip vermilion, buccal mucosa, gingiva
Which area’s leukoplakia show highest chances of dysplasia
Tongue, floor of the mouth
Variants of leukoplakia
Homogenous (most common), granular, speckeled, verrucous
Which type of leukoplakia has highest risk of malignant transformation to Squamous cell carcinoma
Proliferative verrucous leukoplakia
Hyperchromatism, pleomorphism, dyskeratosis
Leukoplakia
Which gender shows high risk of malignancy from leukoplakia
Female
Benign white lesion associated with HIV pts, can occur in immunosuppressed pts
Hairy leukoplakia
Cause for hairy leukoplakia
Epstein-Barr virus
Wrinkled in vertical direction, white asymptomatic patch, bilaterally on lateral surface of tongue
Hairy leukoplakia
Chronic inflammatory mucocutaneous, T cell mediated
Lichen planus
Looks like lichen planus but caused by dental material, stress, medications
Lichenoid mucositis
Most common types of lichen planus
Reticular, erosive
On skin purple, pruritic, polygonal, papules on flexor surface of extremities, genital mucosa, nails
Lichen planus
Common location for lichen planus
Buccal mucosa bilaterally
Most common form of lichen planus
Reticular
Asymptomatic bilateral white papules connect and form network
Reticular lichen planus
Wickham Striae
Lichen planus
Erosive lichen planus only affecting gingiva
Desquamative gingivitis
Erythematous, atrophic areas with central ulceration bordered by thin,white radiating striae
Erosive lichen planus
Symptomatic form of lichen planus
Erosive
Saw tooth appearance of rete pegs, degeneration of basal cell layer Hydropic degeneration
Lichen planus
Civatte bodies, hyaline bodies
Lichen planus
Bandlike infiltration of inflammatory cells
Lichen planus
Common sequela of pts who undergo allogenic bone marrow transplantation
Graft-versus-host disease
Features minic to sjorgan’s syndrome, SLE and scleroderma
Chronic GVHD
Fine reticular network of white striae that mimic oral lichen planus
Graft-versus-host disease
Bone marrow transplant pts have increased risk for
Epithelial dysplasia, squamous cell carcinoma
To prevent GVHD pts preparing for BMT undergo
T cell depletion of graft & prophylactic tx with immunosuppresants
Form of keratosis on hard palate due to heat of pipe/cigar smoking
Nicotine Stomatitis