Neoplasms Flashcards

1
Q

Malignant neoplasm of stratified squamous epithelium, locally destructive growth and distant metastatis

A

Squamous cell carcinoma

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2
Q

Moat common type of oral cancer, risk factor tobacco, invasion

A

SCC

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3
Q

Indurated ulcer with rolled borders, exophytic, endophytic, leukoplakia, Erythroplakia, erythroleukoplakia, loosening or loss of teeth, parasthesia

A

SCC

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4
Q

Most common site for oral cancer

A

Vermillion of lower lip

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5
Q

Most common intra oral site for oral cancer

A

Postero-lateral tongue

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6
Q

Upper or lower lip has good prognosis after SCC

A

Lower

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7
Q

Which site of cancer causes more deaths

A

Cancer of tongue

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8
Q

Metastasis of SCC of tongue

A

Ipailateral side of tongue, submandibular or jugulodigastic nodes at angle of mandible

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9
Q

Second most common intra oral site for SCC

A

Floor of mouth

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10
Q

Least favourable prognosis of SCC

A

Floor of mouth

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11
Q

Very good prognosis of SCC

A

Buccal mucosa along plane if occlusion
Gingiva mandibular posteriors

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12
Q

Chronic sinusitis, bulging of palate, loosening of teeth, parasthesia of cheek

A

SCC of maxillary sinus

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13
Q

Least common site for SCC

A

Nasopharynx- sore throat, nasal obstruction

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14
Q

Oropharyngeal squamous cell carcinoma can occur due to

A

Human Papilloma Virus

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15
Q

Most common carcinogenic types of HpV

A

HPV 16 & HPV 18

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16
Q

Tumor grading. Grows at slower pace, metastasize later, resembles its tissue in origin, shows keratin pearls formation

A

Low grade SCC

17
Q

Poorly differentiated, enlarge rapidly, metastasize early, don’t resemble origin, little to no keratin production

A

High grade SCC

18
Q

Low grade variant of oral SCC

A

Verrucous carcinoma

19
Q

Causes for verrucous carcinoma

A

Tobacco and HPV

20
Q

Whitish diffuse, well demarcated, asymptomatic, thick plaque with papillary or verruciform surface projections

A

Verrucous carcinoma

21
Q

Common low grade skin cancer, locally destructive by invasion but rarely metastatize

A

Basal cell carcinoma/rodent ulcer

22
Q

Most common skin cancer, white adults, fair complexions, males, excessive sun exposure

A

Basal cell carcinoma

23
Q

Non healing, indurated chronic ulcer located primarily on sun exposed areas of head and neck

A

Basal cell carcinoma

24
Q

Basal cell carcinoma tx

A

Mohs micrographic surgery

25
Third most common skin cancer, spread rapidly and deadly form. UV radiation from sun, fair skin, blue or green eyes, red or blonde hair
Malignant Melanoma
26
Definite predilection for palate and the maxillary gingiva/alveolar ridge
Malignant melanoma
27
Most common type of melanoma
Superficial spreading malignant melanoma- flat and irregular shape and color
28
Type of malignant melanoma with poorest prognosis
Nodular melanoma
29
Develops from pre existing lentigo maligna/ hutchinson freckle
Lentigo maligna melanoma
30
Growth phases of malignant melanoma
Radial and vertical Radial: initial growth in horizontal plane, macular flat slightly elevated without metastasis, cure rate 100% Vertical: increase in size, change in color, nodularity and ulceration, curr rate of 70%
31
Vertical growth is characteristic of
Nodular melanoma
32
Abnormal plasma cells that most often build up in bone marrow
Multiple myeloma
33
Skull, vertebrae, ribs, molar ramus most common site. Pain in lumbar or thoracic region. Swelling, pain, loosening of teeth and parasthesia
Multiple myeloma
34
Multiple small punched out radiolucencies on lateral skull radiograph, M spike, bence jobes proteinuria. High calcium, renal problems, anemia, bone problems
Multiple myeloma
35
Malignancy of lymphoid organ tissues, extranodal lymphoid sites in areas known as mucosa associated lymphoid tissue, waldeye’s ring ring of lymphatic tissue formed by two palatine tonsils
Lymphoma