Neoplasms Flashcards

1
Q

Malignant neoplasm of stratified squamous epithelium, locally destructive growth and distant metastatis

A

Squamous cell carcinoma

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2
Q

Moat common type of oral cancer, risk factor tobacco, invasion

A

SCC

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3
Q

Indurated ulcer with rolled borders, exophytic, endophytic, leukoplakia, Erythroplakia, erythroleukoplakia, loosening or loss of teeth, parasthesia

A

SCC

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4
Q

Most common site for oral cancer

A

Vermillion of lower lip

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5
Q

Most common intra oral site for oral cancer

A

Postero-lateral tongue

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6
Q

Upper or lower lip has good prognosis after SCC

A

Lower

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7
Q

Which site of cancer causes more deaths

A

Cancer of tongue

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8
Q

Metastasis of SCC of tongue

A

Ipailateral side of tongue, submandibular or jugulodigastic nodes at angle of mandible

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9
Q

Second most common intra oral site for SCC

A

Floor of mouth

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10
Q

Least favourable prognosis of SCC

A

Floor of mouth

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11
Q

Very good prognosis of SCC

A

Buccal mucosa along plane if occlusion
Gingiva mandibular posteriors

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12
Q

Chronic sinusitis, bulging of palate, loosening of teeth, parasthesia of cheek

A

SCC of maxillary sinus

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13
Q

Least common site for SCC

A

Nasopharynx- sore throat, nasal obstruction

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14
Q

Oropharyngeal squamous cell carcinoma can occur due to

A

Human Papilloma Virus

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15
Q

Most common carcinogenic types of HpV

A

HPV 16 & HPV 18

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16
Q

Tumor grading. Grows at slower pace, metastasize later, resembles its tissue in origin, shows keratin pearls formation

A

Low grade SCC

17
Q

Poorly differentiated, enlarge rapidly, metastasize early, don’t resemble origin, little to no keratin production

A

High grade SCC

18
Q

Low grade variant of oral SCC

A

Verrucous carcinoma

19
Q

Causes for verrucous carcinoma

A

Tobacco and HPV

20
Q

Whitish diffuse, well demarcated, asymptomatic, thick plaque with papillary or verruciform surface projections

A

Verrucous carcinoma

21
Q

Common low grade skin cancer, locally destructive by invasion but rarely metastatize

A

Basal cell carcinoma/rodent ulcer

22
Q

Most common skin cancer, white adults, fair complexions, males, excessive sun exposure

A

Basal cell carcinoma

23
Q

Non healing, indurated chronic ulcer located primarily on sun exposed areas of head and neck

A

Basal cell carcinoma

24
Q

Basal cell carcinoma tx

A

Mohs micrographic surgery

25
Q

Third most common skin cancer, spread rapidly and deadly form. UV radiation from sun, fair skin, blue or green eyes, red or blonde hair

A

Malignant Melanoma

26
Q

Definite predilection for palate and the maxillary gingiva/alveolar ridge

A

Malignant melanoma

27
Q

Most common type of melanoma

A

Superficial spreading malignant melanoma- flat and irregular shape and color

28
Q

Type of malignant melanoma with poorest prognosis

A

Nodular melanoma

29
Q

Develops from pre existing lentigo maligna/ hutchinson freckle

A

Lentigo maligna melanoma

30
Q

Growth phases of malignant melanoma

A

Radial and vertical
Radial: initial growth in horizontal plane, macular flat slightly elevated without metastasis, cure rate 100%
Vertical: increase in size, change in color, nodularity and ulceration, curr rate of 70%

31
Q

Vertical growth is characteristic of

A

Nodular melanoma

32
Q

Abnormal plasma cells that most often build up in bone marrow

A

Multiple myeloma

33
Q

Skull, vertebrae, ribs, molar ramus most common site. Pain in lumbar or thoracic region. Swelling, pain, loosening of teeth and parasthesia

A

Multiple myeloma

34
Q

Multiple small punched out radiolucencies on lateral skull radiograph, M spike, bence jobes proteinuria. High calcium, renal problems, anemia, bone problems

A

Multiple myeloma

35
Q

Malignancy of lymphoid organ tissues, extranodal lymphoid sites in areas known as mucosa associated lymphoid tissue, waldeye’s ring ring of lymphatic tissue formed by two palatine tonsils

A

Lymphoma