Salivary Gland Tumors Flashcards
Most common salivary gland tumor benign
Pleomorphic adenoma
Pleomorphic adenoma common site
85 % in parotid extraorally, if intra oral then posterior palate
Slowly growing, painless and firm mass, smooth and lobulated, on parotid swelling overlying the mandibular ramus
Pleomorphic adenoma
3-4% of Pleomorphic adenoma can go under malignant transformation into
Carcinoma ex Pleomorphic adenoma
Tumors showing more uniform histological pattern
Monomorphic adenoma
Benign salivary gland tumor found on parotid gland, upper lip and buccal mucosa, slow growing, movable mass less than 3 cm, older females histologically basal cell epidermis like
Basal cell adenoma
Uncommon tumor that only occurs in minor salivary glands
Canalicular adenoma
Single layered cords if columnar or cuboidal epithelium, they enclose ductal structures to form long canals
Canalicular adenoma
Benign neoplasm that occurs almost exclusively in the parotid gland
Warthin’s tumor/ papillary cystadenoma lymphomatosum
2nd most common salivary gland tumor, older males
Warthin’s tumor
Glandular and cystic tumor lined by bilayered epithelium with lymphoid stroma
Warthin’s tumor
Ductal epithelium and lymphoid stroma, multiple papillary infoldings that protrude into cystic spaces
Warthin’s tumor
Benign salivary gland tumor comprise 85% of
Parotid tumors
Malignant salivary gland tumors comprise 45% of
Minor salivary glands
Rare but aggressive parotid gland tumors, pain or facial weakness, firm mass irregular borders and infiltration into surrounding tissue, solid tumor without any cystic spaces
Adenocarcinoma
Adenoid cystic carcinoma common in
40-45% in minor salivary glands of palate
Cribriform, swiss cheese, tubular, solid, perineural invasion causing pain, metastases to lungs , bone and brain
Adenoid cystic carcinoma
Most common malignant tumor on minor and major salivary glands
Mucoepidermoid carcinoma
Most common and 2nd most common sites for mucoepidermoid carcinoma
Parotid and palate
Mucus cells and epidermoid cells
Mucoepidermoid carcinoma
2nd most common parotid malignancy and second most common pediatric salivary gland malignancy
Acinic cell carcinoma
Carcinoma from epithelial component of a pre-existing pleomorphic adenoma
Malignant mixed tumors
Both stromal and epithelial elements
Carcinosarcoma ( true malignant mixed tumor)
Second most common malignancy in minor salivary glands, palate lip and buccal mucosa
Polymorphous low grade adenocarcinoma