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Oral Pathology > Vesiculobullous Lesions > Flashcards

Vesiculobullous Lesions Flashcards

1
Q

Spread through infected saliva or active perioral lesions, skin above waist

A

HSV1

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2
Q

Spread through genital zones, sexual contact, skin below waist

A

HSV2

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3
Q

Most common site of latency for HSV 1

A

Trigeminal ganglion

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4
Q

Numerous pinhead vesicles, rapidly collapse to form numerous small red lesions

A

Acute herpetic gingivostomatitis/ primary herpes

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5
Q

Self inoculation of finger in primary herpes can cause

A

Herpetic whitlow

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6
Q

Most common site for recurrence for HSV 1

A

Vermillion border & adjacent skin to lips

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7
Q

Multiple small, erythematous papules form clusters of fluid filled vesicles

A

Recurrent herpes simplex infection

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8
Q

Acantholysis, ballooning degeneration, Tzank cells

A

HSV1

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9
Q

Lipschütz bodies

A

HSV1

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10
Q

Varicella Zoster Virus also known as

A

HHV 3

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11
Q

Pruritic vesicular rash which becomes pustules which hardens & scab over

A

Varicella( chickenpox)

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12
Q

Chickenpox oral lesion found on

A

Palate & buccal mucosa

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13
Q

In childhood common complications of varicella

A

Secondary skin infections, encephalitis, pneumonia

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14
Q

In adults common complication of varicella

A

Pneumonitis, encephalitis

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15
Q

Where does varicella establish latency

A

Dorsal root ganglia

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16
Q

Involves distribution of affected sensory nerve

A

Shingles/ hepes zoster

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17
Q

Only one recurrence and prevalence increases with age

A

Shingles/ herpes zoster

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18
Q

Distinctive unilateral painful vesicles along the distribution of sensory nerve

A

Shingles

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19
Q

Neural necrosis, neuralgia

A

Prodormal herpes zoster

20
Q

15% of herpes zoster progress to chonic

A

Post herpetic neuralgia

21
Q

Hight chances of postherpetic neuralgia if

A

Ophthalmic involvement

22
Q

Shingles complications

A

Ramsey Hunt syndrome

23
Q

Involvement of ipsilateral facial & auditory nerves, facial paralysis, hearing deficits, vertigo

A

Ramsey Hunt syndrome

24
Q

Herpangina caused by

A

Coxsackie A virus

25
Q

Lesions on posterior part of mouth, soft palate, tonsillar pillars, red macules, fragile vesicles rapidly ulcerates

A

Herpangina

26
Q

Vesicular eruptions on palms of hands, soles of feet, mucosa of ant of mouth

A

Hand foot mouth disease

27
Q

Autoimmune mucocutaneous disease- intraepithelial blister formation

A

Pemphigus Vulgaris

28
Q

Breakdown or loss of intercellular adhesion, acantholysis

A

Pemphigus Vulgaris

29
Q

Abnormal production of antibodies directed towards desmosomes

A

Pemphigus Vulgaris

30
Q

Large superficial fragile blister that burst easily

A

Pemphigus Vulgaris

31
Q

Positive Nikolsky sign

A

Pemphigus Vulgaris
Erythema Multiforme
Can be in Mucous Membrane Pemphigoid

32
Q

Suprabasilar vesicles, intra epithelially, row of tombstones, acantholysis, tzank cells

A

Pemphigus Vulgaris

33
Q

Diagnostic tests for Pemphigus Vulgaris

A

Biopsy + Direct Immunoflurescence testing

34
Q

Chicken wire or fish net appearance

A

Pemphigus Vulgaris

35
Q

Chronic blistering oral and ocular mucous membranes

A

Mucous membrane pemphigoid

36
Q

Antibodies attack on hemidesmosomes

A

Mucous membrane pemphigoid

37
Q

Desquamative gingivitis

A

Mucous membrane pemphigoid

38
Q

Most significant complication of Mucous membrane pemphigoid

A

Ocular involvement-> blindness

39
Q

Subepithelial bullae, no acantholysis, no tzank cells, may be nikolsky sign

A

Mucous membrane pemphigoid

40
Q

DIF pattern in mucous membrane pemphigoid

A

Linear pattern

41
Q

Type 3 hypersensitivity reaction

A

Erythema multiforme

42
Q

Target lesions( iris lesions/ bull’s eye)

A

Erythema Multiforme minor

43
Q

Hemorrhagic crusting of vermilion zone of lip

A

Erythema Multiforme

44
Q

Erytherma Multiforme major also known as

A

Stevens-Johnson syndrome

45
Q

Eye lesions(conjunctivitis), genital lesions(balanitis, vulvovaginitis) , stomatitis

A

Erythema Multiforme major

46
Q

Erythema Multiforme major triggered by

A

Sulphonamides

Oral Pathology (18 decks)

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