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phase 3 (1) > Week 9 > Flashcards

Week 9 Flashcards

1
Q

2 autoantibodies in T1DM

A

insulinoma associated antigen 2

glutamic acid decarboxylase

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2
Q

6 mody features

A 
monogenic 
AD
HNF1
over 25
c peptide not low
ab negative
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3
Q

7 pancreatic diabetes

A 
monogenic 
AD
HNF1
over 25
ab negative 
low c peptide
ketones
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4
Q

what causes pancreatic diabetes

A

pancreatectomy
pancreatitis
CF
hemochromatosis

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5
Q

HBA1c target

A

less than 53

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6
Q

6 irregular insulin dosage causes

A 
CHO counting 
pregnant 
pump failure 
administration 
illness
injection sites
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7
Q

4 hypothyroid primary causes

A

hashimotos
post iodine
thyroidectomy
congential

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8
Q

what causes thyroid dysgeneiss

A

TSH receptor

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9
Q

what causes dyshormeogenesis

A

pendrin
pondered syndrome
thyroglobulin
SI s’emporter

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10
Q

treatment of hyperthyroidism

A

beta blocker
carbimazole
propthiouracil
131 idoine

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11
Q

graves treatment

A

alemtuzemab - CD 52

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12
Q

what is iodine induced hypo or hyper

A

jod baedow

wolf chairkoff

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13
Q

what is type 1 amidoarone thyroid disease

A

unmaking previous thyroid disease

give carbimazole

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14
Q

what is type 2 amiodarone thyroid disease

A

destructive thryoidisitis

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15
Q

what is medullary cancer

A

c cells

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16
Q

what is men 2 and 3

A

MTC, phaeo, primary hyperpaprathydoid

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17
Q

5 things for semen analysis

A 
- 1-3 days after last ejactulation 
2-5ml
20-106 sperm 
50% progressive 
over 30% morphology
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18
Q

4 main hypopituatirsm causes

A

head injury
kallmans
genetic
surgery

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19
Q

Kal 2

A

ad

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20
Q

KAL 3

A

ar

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21
Q

KAL 1

A

x linked

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22
Q

5 causes of primary gonadal failure

A 
kleinfilers 
cryporthidiam 
leydig cell failure
ST failure
adult leydig cell failure
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23
Q

4 symptoms of androgen treatment

A 
sweating 
increased hematocrit
prostate
acne
mood
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24
Q

5 primary causes of amenorrhea

A 
rokitansky
turners
kallmans
pituitary disease
low BMI - hypothalamic
25
5 secondary causes of ammenoeha
``` ashermnas PCOS premature ovarian failure prolactinoma pituitary tumour ```
26
2 causes of hirsutism
CAH | PCOS
27
4 symptoms of PCOS
annovualtion hirsutism acne alopecia
28
how to distinguish ovary from adrenal cause of hirusitm
DHEAS
29
most common cause of secondary hypertension
primary hyperaldosteronism
30
2 causes of primary hyperaldosteronism
adenoma or bilateral adrenal hyperplasia
31
2 tests for primary hyperaldoseronism
saline suppression | aldosterone renin ratio
32
treatment of primary hyperaldosteronism
spironolactone or surgery
33
4 tests for cushions
24 hour urinary cortisol cortisol creating ratio dexamthasome suppression test late night salivey cortisol
34
symtoms in boys and girls of CAH
ambiguous genitalai in female | adrenal crisis and early virtualisation in males
35
treatment of CAH
MCR | GCR
36
why late onset CAH and test
increases ACTH drive | synachten test with 17 0hD
37
bichem in adrenal insufficiency
increased na | dreacred K
38
test for adrenal insufficiency
adrenal autoantibodies | renin; aldosterone
39
whipples train
symptoms of hypo low plasma glucose relief after glucose
40
hypoglycemia test
72 hour fast
41
how to distinguish local insulin from diffuse nestiobastlsosi
arterial calcium stimulation
42
MEN type 1
parathyroid ant pituitary eneteropancreatic endocrine cells
43
cushings treatment
ketokonazole
44
carcinoid syndrome
``` release serotonin flushing dihorrea asthma right heart vaulvar lesions ```
45
graves gives what to palms
palmar erythema
46
how to test for carcinoid syndrome
5H1AA
47
diffuse iodine uptake
multinodialr goitre
48
irregular iodine uptake
multinodualr goitre
49
reduced uptake
thyroiditis
50
3 ketoacidosis symptpms
capillary ketone testing urine ketone serum bicarb
51
hypoadrenalism treatment
hydrocortisone - glcocorticoid | fludrocortisone - mineral cooridoic
52
2 physical exam signs in hypoadrenalism
hyperpigmentation | postural hypotension
53
4 anthyroid drugs side effects
``` rash itch fever hair loss nausea` ```
54
DPP4 example
linagliptin
55
GLP example
liraglitide
56
sulphonylurea example
gliclazide
57
SGLT 2 inhibitor example
emplaglobflozin
58
thiazolodione example
pioglitazone
59
read over side effects
ro

phase 3 (1) (16 decks)

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