Week 6/7 Flashcards
3 antibiotic use
- guided
- prophylatic
- empirical
b lactam activity
inhibits cross linking of peptidoglycan cell wall
most common beta lacatam
staph aureus
all beta lacatams given IV minus amox and flucoloc
3 penicillins
bezyl
amox
fluclox
2 beta lacatmas
coax
tazobactam
1 monobactam
aztreonam
1 cephalosporin
cefriaxone
1 crabapenem
meropenum
3 Vanc symptoms
red man
oto
npwhro
3 50 s ribosomal subunit
cloramphenical
clindamycin
macorlides
3 macorlides
erythromycin
clarithromycin
azithromycin
2 30s ribosomal subunits
aminoglycosides - gent
tetra - doxy
macrocodes act on
atypicals
5 atypical
legionella mycoplasma chlamidya coxiella chalmydophila
anaerobes
clindamycin
3 adverse effects of macrocodes
dihorra
QT prolonged
hearing loss
4 Cs
clinda
cephalo
cipro
coax
cholarmphenical synomptoms
bone marrow suppression
aplastic anaemia
optic neuritis
chroamphenical is for
bacterial meningitis
nitrofurantoin consequence
nhemolytic anamaiea
CAP dugs
amox 1g 8 hourly IV
clarity if allergy
serve CAP
coamox
with clarithro if atypical
septic arthritis
flcolax and rifampicin
pyelonephritis
gentamicin
STTI
amor or calrithro if allergy
biliary sepsis
amox
gent
metro
5 bacterial AMR
inactivating enzymes alternative enzymes efflux pumps decreased uptake target alterations
3 extrinsic resistance
transduction - tetracycline R
transformation - penicillin R
conjugation - beta lacatmases in enterobacter
if respisnat to penicillin ND cephalosporin
ESBL
3 typical CAP
hemphilus
mortadella catharalis
streptococcus pneuma
4 atypical CAP
mycoplasma
legionella
chalmydophila pneumonia
chamlydophila psittaci
who gets hemphilius influenza
older with underlying
5 other homophiles symtoms
otiits conjunctivitis sinusits penumoina meningitis
8 mycoplasma pneumonia symtoms
fever itredness headache sweating arthritis guillane barre hemolysis erythema multiform
legionella presentono
non specific
antigen tests
q SOFA
RR over 22
altered mental state
systolic less than 100
CURB 65
confusion urea over 7 respiratory over 30 BP less than 60 or 90 over 65
plus multiloabr consolidation
features of atypical pneumonia
non specific