Week 4

Question 1

6 microscopic features of fibrocystic change

Answer 1

small and large cysts
epithelial hyperplasia
adenosis
micro calcification
apocrine metaplasia

Question 2

symotom of introduction papilloma

Answer 2

nipple discharge

Question 3

2 symptoms of periductal mastitis/ mamamry gland duct ectasia

Answer 3

nipple retraction or discharge
redness, swelling, blocked, inflamed
breast abcess

Question 4

breast cancer screening

Answer 4

50-70 every 3 years

Question 5

stage vs grade

Answer 5

stage = TNM
grade = 1-3 depending on differentiation

Question 6

NPI

Answer 6

size of the tumour;
the number of involved lymph nodes
the grade of the tumour.

Question 7

features of lobular carcinoma

Answer 7

small
bland
discohesive

Question 8

screening for cervical

Answer 8

25-50 - 3 yearly

50-65 - 5 yearly

Question 9

early genes in HPV

Answer 9

E1-7

interact with intracellular molecules to interfere with cell proliferation to replicate virus

Question 10

late genes

Answer 10

L1-L2

encode capsid proteins

Question 11

koyocytosis

Answer 11

large nuclear field

Question 12

4 features of SCC of vulva associated with VIN

Answer 12

below 60
lower GI neoplasia
HPV 16/18
warty

Question 13

4 features of SCC of vulva associated with dermatoses

Answer 13

over 60
well differentiated
keratinising
not HPV or VIN

Question 14

ovarian stroma hyperplasia 4 features

Answer 14

post menopause
uniformly enlarged
stromal hyperthecosis if stromal cells present
white/yellow nodules

Question 15

most common cause of dyskaryosib

Answer 15

CIN

Question 16

HPV management

Answer 16

loop biopsy

Question 17

highest Allred score

Answer 17

8

Question 18

a nuclear stain for proliferation

Answer 18

K 67

Question 19

CDX2

Answer 19

GI tract

Question 20

C1 - C5

Answer 20

insufficent
benign 
atypia prob benign
atripya prob malignant
malignant

Question 21

3 means

4 means

Answer 21

3. retroperitoneal

4. PE, lung spleen