week 3 Flashcards

1
Q

3 genetics in myeloproliferative

A

JAK 2
calreticulin
positive ET

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2
Q

3 examples of myeloproliferative

A

CML
myelofibrosis
MPD
PRV

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3
Q

what is essential thrombocytosis

A

over 600x109

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4
Q

medication for JAK 2

A

ruxolitinib

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5
Q

international prognostic scoring system

A

blasts karyotype cyrpenia

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6
Q

who can you autologous transplant

A

HL, NHL, myeloma

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7
Q

who can you allograft transplant

A

acute, chronic leukaemia
relapsed lymphoma
heerediarty disorders

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8
Q

which vitamin deficiency gives demylenimation of pyramidal tracts

A

B12

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9
Q

2 other causes of macrocytosis

A

reticulocytosos

cell wall abrnomailites

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10
Q

what is TTP

A

mutation in MMp for breaking down VWF

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11
Q

what is ITP

A

IgA breakdown of platelets

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12
Q

is extravascular/intravascualr cold

A

intravascular

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13
Q

reed Sternberg

A

HL

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