Week 8 - Learning Flashcards

1
Q

Process by which experiences change our nervous
system and hence our behaviour

A

Learning

also

most common

CONDITIONED EMOTIONAL RESPONSE

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2
Q

Types of Conditioning

A

■ Classical Conditioning
■ Operant Conditioning
■ Statistical Learning
■ Perceptual Learning
■ Relational Learning

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3
Q

Who was the main founder of Early Conditioning

A

Ivan Pavlov

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4
Q

Main contributor/founder of Behaviourism (/ Classical Conditioning)

A

John B. Watson
(1849-1936)
- Nobel Prize in
Physiology
“Father of Behaviourism”

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5
Q

Can a conditioned behaviour be de-conditioned?

A

True !
Known as Extinction

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6
Q

After training, excitation in CS center
flows to UCS center, which elicits the
same response as UCS

A

Pavlov’s proposal

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7
Q

physical representation of what
has been learned

A

Engram

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8
Q

_____ conducted an experiment to see if there is Localization with Engrams, the experiments showed that ______…

A

Karl Lashley (1890-1958)

■ Reasoned that if memories were connections between
brain areas, they could be severed with a knife
■ Trained rats on mazes and tasks, then made cuts to the
cortex to try to disrupt performance
HOWEVER
Cuts did not impair performance
– Learning did not depend on
connections across the cortex
■ Learning did not depend on a single area of the cortex
– Taking out a chunk of cortex impaired performance, but it was
about the chunk taken, not the cortical area itself

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9
Q

What two key principles did Karl Lashley (1890-1958) propose about the nervous system in his study of localization of engrams in the brain

A
  1. Equipotentiality: all parts of the cortex contribute equally to
    complex functioning behaviors (e.g., learning) and any part can
    substitute for any other
  2. Mass action: the cortex works as a whole and more cortex is better
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10
Q

Examples of Engram

A

■ Tone (CS)
■ Air-puff (UCS)
■ Eye-blink (UCR – CR)

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11
Q

Who was known as the “mother of behaviour therapy”, and make great contributions to “desensitization”

A

Mary Cover Jones
(1897-1987)
■ Mother of
Behaviour Therapy

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12
Q

Laboratory Study of Fear: The Case of Peter (1924)

A

– Rabbit = Fear
– Rabbit = tasty food = fear reduction
– Direct conditioning (a.k.a., desensitization)

Mary Cover Jones
(1897-1987)
■ Mother of
Behaviour Therapy

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13
Q

**Learning is instantiated in the _______
+
Extra Engram Brian Area Facts

A

lateral interpositus
nucleus (LIP)
**

■ Red nucleus is required to demonstrate the
learning (i.e., execute the eye-blink)

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14
Q

Who was the founder of Operant (Instrumental)
Conditioning

A

BF Skinner (1904-
1990)

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15
Q

“Giving something bad”

A

Positive Punishment

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16
Q

“Taking away something bad”

A

Negative Reinforcement

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17
Q

“Giving something good”

A

Positive Reinforcement

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18
Q

“Taking away something good”

A

Negative Punishment

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19
Q

A series of positive / negative reinforcements and punishments are central to ________________ theory of ___________ conditioning

A

BF Skinner (1904-
1990)

Operant (Instrumental)

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20
Q

The desired behavior is reinforced every
single time it occurs.

A

Continuous Reinforcement

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21
Q

Once the response is established. The
response is reinforced only part of the time.
■ Fixed-ratio or Variable ratio (# responses)
■ Fixed interval or Variable interval (amount of time)

A

Intermittent Reinforcement

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22
Q

Difference between Classical and Operant Conditioning

A

Classical conditioning involves learning through associations between stimuli, while operant conditioning involves learning through the consequences of behavior.

Classical conditioning focuses on involuntary, reflexive responses, whereas operant conditioning focuses on voluntary, goal-directed behaviors

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23
Q

The ability to perceive and
learn regularities
■ E.g, in language, such as the
speech sounds that comprise
a word

A

Statistical Learning

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24
Q

learning to “recognize” things

A

Perceptual Learning
(Who is this? What is this? Who sing’s this song?)
Mechanisms: Attention weighting; Imprinting; Differentiation; Unitization

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25
Q

*Most learning is more complex than simple Stimulus-Response
associations
*Involves learning the temporal and spatial relationships among objects
and events
This multifaceted type of learning is known as

A

Relational Learning

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26
Q

The process of short term memory being formed into long term memory

A

Consolidation

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27
Q

Memory which is:
■ Limited capacity
■ Fades without rehearsal
■ Usually more contextual
detail than LTM

A

Short Term Memory (STM)

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28
Q

Memory which is:
■ Unlimited capacity
■ Indefinite storage time
■ Stimulated with cue/hint,
unlike STM

A

Long Term Memory (LTM)

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29
Q

In memory the way we get information through our senses can be known as our

A

“Sensory Register”

30
Q

Within Long Term Memory (LTM) there are two main sub categories

A

Explicit Memory and Implicit Memory

31
Q

Long Term Memory that is unconscious

A

Implicit Memory

32
Q

Long Term Memory that is conscious

A

Explicit Memory

33
Q

Memory that represents skills and tasks (ex. how to ride a bike)

A

Procedural Memory

34
Q

Memory that represents overall information about facts / events

A

Declarative Memory

35
Q

Two Subcategories of Declaritive Memory

A

Episodic Memory and Semantic Memory

36
Q

Memories of Events and Experiences / specific events that you’ve experienced

A

Episodic Memory

37
Q

Memories of Fact and Knowledge / object knowledge learned over many interactions

A

Semantic Memory

38
Q

Is Procedural Memory Conscious or Unconcious?

A

Unconscious

39
Q

Is Declaritive Memory Conscious or Unconcious?

A

Conscious

40
Q

The __________ is Active during:
– Memory formation
– Memory recall
– Imagining future events

and is Vital for declarative/episodic memory

A

Hippocampus

41
Q

The main center / area for memory in the brain is the _____________

A

Medial Temporal Lobe (Hippocampus, Basal Ganglia)

42
Q

Maguire et al., 2000

A

In visual spatial memory
– More years = greater
Hippocampus volume

43
Q

Spatial Memory cells that fire in response to spatial
locations and temporal information

A

Place Cells and Time cells located in the Hippocampus

44
Q

Spatial Memory Cells that hexagonal grid forming a coordinated system that allows for spatial navigation.

A

Grid Cells located in the Entorhinal cortex (ERC)

45
Q

What does the Entorhinal cortex (ERC) do in memory

A

plays a critical role in communications between the hippocampus and cortical association and limbic areas

46
Q

What brain part is involved in implicit learning of patterns
and habits

A

Basal Ganglia

47
Q

The information and memories individuals accumulate that
creates a unique identity and a person sense of continuity

A

Autobiographical Memory
Contains two components of memory:
– episodic (specific personal events)
– semantic (general world knowledge)

48
Q

What is memory loss known as

A

Amnesia

49
Q

Two main types of Amnesia

A

Retrograde and Anterograde

50
Q

Can’t remember something / life before
an injury

A

Retrograde
Amnesia

51
Q

Can’t make new memories after an injury

A

Anterograde
Amnesia

52
Q

the inability of humans to
remember episodic experiences that occurred during
the first few years of life (generally 0–3 years)

A

Infantile Amnesia

53
Q

What explains infantile amnesia?

A

Immaturity of hippocampal systems
– Critical period - hippocampus is highly responsive to environmental
experiences might impede storage of episodic details.

54
Q

True / False: Do Animals have Infantile Amnesia

A

TRUE
animals also exhibit
infantile amnesia

55
Q

Healthy people report a failure to re-
experience or recollect specific events
from their past, although their
memory for factual information about
themselves and the world is intact

A

Severely Deficient Autobiographical
Memory (SDAM)

56
Q

inability to visualize in the
minds eye.

A

Aphantasia

57
Q
  • Thiamine deficiency (common in alcoholism)
  • Loss of neural activity throughout the brain, esp. dorsomedial
    thalamus
  • Hallmark: confabulation (“honest lying”)
A

Korsakoff’s syndrome

58
Q

Dementia

A
  • Semantic Dementia: Anterior temporal cortex
  • Frontotemporal Dementia (FTD): Frontal and anterior temporal
  • Alzheimer’s Disease: Hippocampus
59
Q

“Any two cells or systems of cells that are repeatedly active
at the same time will tend to become ‘associated’, so that
activity in one facilitates activity in the other.”

A

Hebb’s Rule

60
Q

Basic mechanism for synaptic plasticity
– increase in synaptic efficacy arises from
presynaptic cell’s repeated and persistent stimulation of
the postsynaptic cell.

A

Hebb’s Rule

61
Q

“Cells that fire together wire together!”

A

Hebb’s Rule

62
Q

The repeated and persistent stimulation of C by A
increases the synaptic efficiency between them.

A

Hebbian Synapse

63
Q

Repeated and persistent stimulation of a particular synapse
makes it more responsive to new input of the same type =
leaving the synapse potentiated

A

Long-term potentiation

64
Q

In Long-term potentiation: only synapses on a cell that
have been highly active become
strengthened

A

Specificity

65
Q

In Long-term potentiation: simultaneous stimulation by
two or more axons produces LTP much
more strongly than does repeated
stimulation by a single axon

A

Cooperativity

66
Q

In Long-term potentiation: pairing a weak input with a
strong input enhances later responses to a
weak input

A

Associativity

67
Q

Three aspects of Long - Term Potentiation at the neural level

A
  1. Specificity
  2. Cooperativity
  3. Associativity
68
Q

Low-frequency stimulation of the synaptic input to a cell can
decrease rather than increase their strength

A

Long-term depression (cell)

69
Q

How does LTP happen at the
cellular level?

A
  1. LTP depends on changes at glutamate synapses.
    – Also GABA synapses, to a lesser extent
  2. Two types of glutamate receptors
    – AMPA receptors
    – NMDA receptors
    both are Ionotropic Receptors = Receptor with binding site and ion chanel.
  3. ■ Glutamate attaches to both receptors.
    ■ AMPA Receptor: opens a channel to let sodium ions enter.
    ■ NMDA Receptor: opens the channel only when the magnesium ions dislodge.
  4. ■ AMPA receptors repeatedly stimulated = enough sodium enters to depolarize the dendrite’s membrane.
    ■ This displaces the magnesium ions = enables glutamate to open the NMDA receptor
    – Sodium and calcium enter
  5. ■ Changes to the Postsynaptic Neuron:
    – Entry of calcium through the NMDA channel triggers further changes.
    – Activation of a protein (CamKII) sets a series of events in motion.
    ■ More AMPA receptors are built and dendritic branching is increased.
    ■ These changes potentiate the dendrite’s future responsiveness
    to incoming glutamate

– Stimulation of a postsynaptic cell causes the release of a
retrograde transmitter that travels back to the presynaptic
cell to cause the following changes:
■ Decrease in action potential threshold
■ Increase neurotransmitter release
■ Expansion of the axons
■ Transmitter release from additional sites

70
Q

True / False: Theoretically, a drug that enhanced LTP might improve memory.

A

True
Nearly all the products marketed so far to improve memory act
as stimulants or by improving overall health.
– Caffeine
– Ritalin
– Adderall
– Modafinil
Enhance learning by increasing arousal
- Helpful for people with low arousal

71
Q

____________ is a form of neuromodulation that uses constant, low direct current delivered via electrodes on the head

– Promising results for treating depression, chronic pain,
Parkinson’s disease, and other conditions
– Possibly it helps people improve attention and memory
– Sometimes improves performance on one task while impairing
another

A

Transcranial direct current stimulation