week 8 immunity Flashcards

1
Q

what is innate

A

non specific components ( cellular or chemical)

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2
Q

what is adaptive

A

specific cellular or chemical component

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3
Q

2 arts of adaptive immune system

A

cell-mediated and humoral

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4
Q

what is the cells called which kill virus-infected cells and tumor cells in adaptive component

A

T CELLS

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5
Q

what is the humoral cell which kill bacteria and virus and tissue repair

A

b cells - produce antibodies and complement cascade

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6
Q

what is the innate cell mediated cell which kill virus and tissue repair

A

neutrophils monocytes

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7
Q

what type of innate cell is cell mediated and kills tumors

A

natural killer cells

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8
Q

what does the skin do

A

stops microbes before infection - the physical barrier

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9
Q

other examples of physical barriers

A

saliva, mucosal membranes, stomach acid, gut barrier, flushing of urine, tears and coughing and sneezing

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10
Q

whats another name for a leukocyte

A

white blood cell

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11
Q

what are the 2 types of lymphocytes

A

T and b cells

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12
Q

monocytes are what in the blood and do what

A

3-9% and consume microbes

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13
Q

what makes up 60% of the blood

A

neutrophils

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14
Q

what are neutrophils

A

an innate - rapid responder to infection and stress and eat/ engulf phagocytes and kill using toxic molecules

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15
Q

what is a phagocytes

A

microbe

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16
Q

what is a natural killer

A

innate, destroy cancer and viruses using cytokines

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17
Q

what proteins travel as inactive proteins in the blood from the liver

A

complement proteins

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18
Q

what do complement proteins recruit

A

phagocytes to site vai chemical gradients

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19
Q

cytokines are released from where

A

innate immune cells to coordinate immune response

20
Q

dendric cells process parts of foreign bodies and present the antigen to what cells

A

T and B cells

21
Q

T and b cells are types of what cells

A

lymphocytes

22
Q

B cells are humoral or cell mediated

A

humoral

23
Q

T cells are cell mediated or humoral

A

cell mediated

24
Q

b cells come from where

A

bone marrow

25
Q

what can b cells do

A

differentiate into different plasma cells and make antibodies

26
Q

what do t cells release

A

cytokines - kill virus

27
Q

t and b cells are specific and have …

A

memories and can reencounter antigens - like a vaccine

28
Q

60-70% of t cells are what

A

helper cells

29
Q

what do helper cells do

A

coordinate immune responses by recruiting other t and b cells for damage or infection sites

30
Q

what percent of t cells are cytotoxic t cells

A

30-40%

31
Q

what do cytoxic t cells do

A

identify antigens and infected and tumor cells

32
Q

how do we measure immune function

A

movement of immune cells towards bacteria or virus

33
Q

the release of molecules reflecting immune response with antimicrobial properties example

A

saliva with enzymes - phagocytosis - isozyme

34
Q

what is phagocytosis

A

ingestion of bacteria or virus by phagocytes

35
Q

exercise evokes a ,marked immune response causing what

A

increase leukocytes in blood and there is an increase post exercise

36
Q

exercise increases shear stress, sympathetic drive and epe as well as what blood flow control

A

vasoconstriction

37
Q

exercise induces a strong innate immune response involving what cells

A

monocytes, neutrophils and macrophages

38
Q

what do neutrophils release

A

proteins and they terminate muscle repair

39
Q

how do the nuetrophils proteins terminate muscle repair

A

movement of immune cells, anti microbial defense and muscle fiber breakdown and regen

40
Q

5 effects post exercise on immune system

A

infections, severity, decrease
anti body production, wound healing, surveillance of canc er and response to vaccines increase

41
Q

indirect improvements of immunity lead to

A

decrease in weight loss - adipose tissue and less inflammation as well as improved vascular health

42
Q

exercise for elderly decreases

A

natural decline

43
Q

exercise helps which elderly functions

A

auto immune, cv , neuro and metabolic

44
Q

tumor growth and exercise are linked yes or no

A

yes

45
Q

under and over training impact immune system yes or no

A

yes