week 8 altitude Flashcards

1
Q

exposure of hypoxia causes a reduction in

A

arterial pressure

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2
Q

the disruption of homeostatic and arterial pressure triggers what

A

neurocrine response that regulates adjustments to physiological systems

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3
Q

what is hypoxia

A

low pO2

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4
Q

what is normoxia

A

normal pO2

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5
Q

what is hyperoxia

A

high po2

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6
Q

what is hypoxaemia

A

low o2 in blood

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7
Q

what is boyles law

A

gas volume is inversely proportional to its pressure

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8
Q

immediate changes of altitude occur to ensure what

A

more o2 molecules

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9
Q

what are effects of short term adjustments to altitude

A

hyperventilation (chemoreceptors, lower alveolar pressure, raises alveolar o2, and lowers alveolar CO2 and causes alkalosis and diuresis

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10
Q

What CV affects short term in adjustments

A

increased resting hr and cardiac output

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11
Q

is there a defined difference in terms of altitude versus sea level

A

yes

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12
Q

how is the hr effected during max exercise in altitude

A

cardiac strain is reduced due to limited max hr due to parasympathetic ns during exercise

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13
Q

what is reduced during max exercise in atitude

A

lactate levels - lactate paradox as well as max hr

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14
Q

what limits max hr during max exercise

A

activation of para sns - the blockade

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15
Q

what is the parasympathetic blockade

A

glycopyrrolate - which restores max hr response to exercise

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16
Q

at altitude partial pressure is increased or decrease of o2

A

reduced

17
Q

vo2 max reduces or increases when increasing altitude

A

reduces

18
Q

ventilation is lower or higher during exercise

A

higher

19
Q

what is the fick equation

A

vo2 = cardiac output X a-Vo2 difference

20
Q

why does co fall in response during submaximal exercise

A

more o2 in blood improving extraction and less cardiac strain

21
Q

what is the primary blood change during altitude

A

polycythemia due to an increase in erythropoietin

22
Q

what is polycythemia

A

increase in red blood cells

23
Q

what is epo

A

erythropoietin is a hormone increasing red blood cells from the liver

24
Q

what does an increase of blood cells mean ..

A

more o2 delivered - 260ml compared to 200ml - extream is 310ml

25
Q

decreased plasma volume in blood helps what

A

hemoglobin

26
Q

hyperventilation causes ..

A

alkalosis and a bohr shift

27
Q

how are capillaries effected

A

increase

28
Q

myoglobin increases or decreases

A

increases

29
Q

aerobic enzymes increases or decreases

A

increases

30
Q

muscle mithocondrai increases or decreases

A

unlikey

31
Q

lactate consumption and oxidation by active muscle increases or decreases

A

increases

32
Q

2 long term effects of pulmonary acid base

A

hyperventilation and excretion of base via kidneys

33
Q

2 effects of haematologic

A

decreased plasma v and increased haemaoctrit and rbc number

34
Q

5 local longer adjustments

A

the increased enzyme, loss of weight and lean mass and cappilliarizaton of skeletal muscle

35
Q

blood viscosity is effected true or false

A

true

36
Q

living at a high altitude can elicit more red blood cells

A

true

37
Q

negative effects

A

less muscle mass and increased ventilatory response, cv changes and loss of training intensity