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Blood Module - 3rd year > week 5 extra Q's > Flashcards

week 5 extra Q's Flashcards

(does anyone even read this?

1
Q

Which of the following is expressed by B cells?

a. C3
b. C5
c. C19
d. C49

A

c. C19

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2
Q

When does Ig heavy chain gene rearrangement start?

a. pre-B
b. pro-B

A

b. pro-B

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3
Q

Which of the following is the first immunoglobulin to appear on B cell surface?

a. IgM
b. IgG
c. IgD
d. IgA

A

a. IgM

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4
Q

Which of the following B cells handle blood-borne antigens?

a. B cells in the mucosal system
b. B cells in the BM
c. B cells in the lymph node
d. B cells in the spleen

A

d. B cells in the spleen

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5
Q

When does Ig light chain gene rearrangement start?

a. pre-B
b. pro-B

A

a. pre-B

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6
Q

Which of the following helps thymocyte precursors develop in BM?

a. IL-5
b. IL-6
c. IL-7
d. IL-8

A

c. IL-7

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7
Q

What’s the state of T cells when they enter the thymus?

a. double positive
b. triple positive
c. double negative
d. triple negative

A

d. triple negative

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8
Q

How do we delete self-reactive T cells?

a. positive selection
b. negative selection

A

b. negative selection

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9
Q

Which of the following recognizes class I HLA?

a. T cells
b. B cells

A

a. T cells

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10
Q

Which of the following helper cells help activate macrophages?

a. Th1
b. Th2

A

a. Th1

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11
Q

Which of the following make holes in bacterial cells?

a. granzymes
b. perforin
c. cytokines

A

b. perforin

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12
Q

Which of the following is more likely to get a lymphoma?

a. a person with a bacterial infection
b. a person with celiac disease

A

b. a person with celiac disease

chronic stimulation makes more lymphoid cells and that makes mutation more likely

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13
Q

Which is more common?

a. hodgkins lymphoma
b. non-hodgkins lymphoma

A

b. non-hodgkins lymphoma

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14
Q

Which of the following is low grade?

a. follicular lymphoma
b. diffuse large B cells lymphoma

A

a. follicular lymphoma

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15
Q

Which of the following commonly has extranodal involvement?

a. follicular lymphoma
b. hodgkins lymphoma
c. diffuse large B cells lymphoma

A

c. diffuse large B cells lymphoma

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16
Q

Which of the following is more common?

a. follicular lymphoma
b. hodgkins lymphoma
c. diffuse large B cells lymphoma

A

b. hodgkins lymphoma

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17
Q

Which of the following is often asymptomatic?

a. follicular lymphoma
b. hodgkins lymphoma
c. diffuse large B cells lymphoma

A

a. follicular lymphoma

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18
Q

Which of the following has Reed-Sternberg cells?

a. follicular lymphoma
b. hodgkins lymphoma
c. diffuse large B cells lymphoma

A

b. hodgkins lymphoma

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19
Q

Which of the following occurs due to a translocation of t(14;18)?

a. follicular lymphoma
b. hodgkins lymphoma
c. diffuse large B cells lymphoma

A

a. follicular lymphoma

20
Q

Which of the following occurs due to a translocation of t(8;14)?

a. follicular lymphoma
b. hodgkins lymphoma
c. burkitts lymphoma

A

c. burkitts lymphoma

21
Q

Which of the following identifies ALL?

a. auer rods
b. basophilia
c. arthralgia
d. well’s syndrome

A

c. arthralgia

22
Q

Which of the following is most likely occurs in a chid thats 4 years old?

a. ALL
b. CLL

23
Q

Which of the following is a characteristic of CLL?

a. auer rods
b. basophilia
c. arthralgia
d. well’s syndrome

A

d. well’s syndrome

24
Q

Which of the following is most likely occurs in 70 y/o man?

a. ALL
b. CLL

25
Q

Which of the following is a characterized by smudge cells?

a. ALL
b. AML
c. CML
d. CLL

26
Q

Which of the following is a characterized by basophilia?

a. ALL
b. AML
c. CML
d. CLL

27
Q

Why do patients with MM have a hypercalcemia?

a. because the infections they aquire increase bone resprption
b. kidneys get damaged and release hormones that increase bone resprption
c. IL-6 is activating osteoclasts
d. IL-5 is activating osteoclasts

A

c. IL-6 is activating osteoclasts

28
Q

Which of these tests is used to determine the type of M protein?

a. immunofixation
b. serum protein electrophoresis
c. urine protein electrophoresis

A

a. immunofixation

29
Q

Patient comes in with bone pain and anemia. PBS reveals rouleaux formation. Which of the following is most likely?

a. CML
b. MM
c. AML

30
Q

Which of the following is true about MGUS?

a. serum level must be more than 30g/l
b. all MM patient had it
c. its treated with immunosuppressants

A

b. all MM patient had it

31
Q

Which of the following is the most immunoglobulin to be excessivly made in plasma cell myeloma?

a. IgM
b. IgG
c. IgA
d. light chain only

32
Q

Which of the following is mainly diagnosed via biopsy?

a. amyloidosis
b. MM
c. CML
d. MGUS

A

a. amyloidosis

33
Q

Which type of plasmacytoma tumor is more likely to develop into MM?

a. soft tissue tumor
b. skeletal tumor

A

b. skeletal tumor

34
Q

What is the precentage of people with MGUS that will develop plasma cell neoplasm?

a. 10%
c. 15%
d. 20%
d. 25%

35
Q

patient comes in with renal failure and a spontaneous fracture, Which is most likely?

a. amyloidosis
b. MM
c. burkitt’s lymphoma
d. MGUS

36
Q

Patient comes in with facial swelling. PBS shows lymphocytes that have vacuoles in them. Which is most likely?

a. amyloidosis
b. MM
c. ALL
d. CLL

37
Q

Which of the following has too many lymphocytes and smudge cells present?

a. ALL
b. lymphomas
c. CLL
d. MM

38
Q

Which of the following has too many follicules in lymph nodes?

a. follicular lymphomas
b. hodgkins lymphomas

A

a. follicular lymphomas

39
Q

Which of the following has RS cells and too few follicules in lymph nodes?

a. follicular lymphomas
b. hodgkins lymphomas
c. CLL
d. MM

A

b. hodgkins lymphomas

40
Q

Which of the following recruit neutrophils?

a. Th1
b. Th2
c. Th17
d. Th18

41
Q

Which of the following mutations lead to burkitts lymphpma?

a. t(14,18)
b. t(18,14)
c. t(8,14)
d. inv(16)

A

c. t(8,14)

42
Q

Which of the following mutations lead to follicular lymphpma?

a. t(14,18)
b. t(18,14)
c. t(8,14)
d. inv(16)

A

a. t(14,18)

43
Q

Which of the following mutations lead to hodgkins lymphpma?

a. t(14,18)
b. t(18,14)
c. t(8,14)
d. inv(16)

A

b. t(18,14)

44
Q

Immunotyping revealed cells with CD23 on them, which is most likely?

a. ALL
b. AML
c. CML
d. CLL

A

d. CLL

its the activation marker

45
Q

Patient comes in with infections due to constant leukocytosis and a complaint of fatigue and sensitivity to bugs. Which is most likely?

a. ALL
b. AML
c. CML
d. CLL

46
Q

Which of the following mutations lead to ALL?

a. t(14,11)
b. t(18,14)
c. t(8,14)
d. inv(16)

A

a. t(14,11)

Blood Module - 3rd year (16 decks)

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