Week 5: Acne

Question 1

Patho of Acne

Answer 1

1) hair becomes hyper-keritinized (thicker)
2) sebaceous glands produce extra sebum, and this along with dead skin cells become sticky and get stuck around the thicker hair follicle and form a plug
3) produces a comedone

Question 2

2 types of comedones

Answer 2

1) Open (blackheads)

2) Closed (whiteheads)

Question 3

3 Types of Acne

Answer 3

1) Mild - open and closed comedones
2) Mild to Moderate - papules, pustules, or both
3) Moderate to Severe - Nodules and cysts

Question 4

1 causative agent of acne

Answer 4

P. Acnes (Propionibacterium acnes)

Question 5

Treatment of acne

Answer 5

1st line- topicals (mono or combo therapy for mild)
** try a couple before moving to 2nd line
- topical benzoyl peroxide
- topical retinoids
- topical antibiotics
2nd line - oral antibiotics
3rd line - Accutane

Question 6

Treatment of mild noninflammatory comedonal acne

Answer 6

• topical - benxoyl peroxide then topical retinoid

Question 7

Treatment of moderate inflammatory papulopustular acne

Answer 7

• add topical antibiotic

Question 8

Treatment of severe inflammatory acne

Answer 8

• oral antibiotic combined with topical combination therapy - topical antibiotic and/or retinoid
• if ineffective - start accutane