Week 5 Flashcards
What is chronic, stable angina?
Fixed stenosis
Demand led ischaemia
Predictable
Safe
What is an acute coronary syndrome?
Any acute presentation of coronary artery disease
Dynamic stenosis
Supply led ischaemia
Unpredictable
Dangerous
In the platelet cascade, how are activators such as ADP released?
Degranulation
What is the first line investigation ordered in a patient with a suspected heart attack?
ECG
Check for ST elevation, T wave inversion and Q waves
What leads show an inferior MI?
II
III
AVF
What leads show an anterior MI?
V1-V6
What leads show an anteroseptal MI?
V1-V4
What leads show an anterolateral MI?
I
AVL
V1-V6
What investigations should be ordered in a suspected MI?
ECG
Cardiac enzymes - Creatinine kinase
Protein marker - troponin
What is the treatment for a STEMI?
Analgesia (diamorphine IV)
Anti-emetic IV
Aspirin
Clopidogrel
GTN
Oxygen if hypoxic
Primary angioplasty
What does troponin do?
Binds calcium and actin
It facilitates contraction
What do capillaries do?
Deliver O2 and nutrients to tissues
Remove metabolites from cells
What are the forces favouring capillary filtration?
Capillary hydrostatic pressure
Interstitial fluid osmotic pressure
What are the forces opposing capillary filtration?
Capillary osmotic pressure
Interstitial fluid hydrostatic pressure
What does heart failure do to the Frank Starling curve?
Shift it to the right