week 2 teaching: connective tissue Flashcards
four functions of connective tissues
packaging and dividing
providing support
energy storage
space filling
what does the function of a connective tissue depend on
its composition and structure
types of connective tissue
fibrocollagenous
adipose
cartilage/ bone
blood
types of fibrocollagenous connective tissue
dense connective tissue
-regular
-irregular
areolar (loose)
reticular
cells of connective tissue always derived from
messenchynmal stem cell lineage
fibroblasts
main cell of fibrocollagenous connective tissue
mono-nucleated cells
adundant RER -
secrete precursors of collagen, elastin and proteoglycans
what does abundant RER mean for a cell
active in terms of producing, packaging, functionlising and excreting proteins and proteoglycans
dense/ regular fibrocollagenous cells
e.g tendon
parallel collagen fibres, all aligned in single direction
withstand force from single direction
dense/ irregular fibrocollagenous tissue
e.g dermis
interwoven collagen and elastin fibres
withstand forces from multiple directions
areolar (loose) fibrocollagenous connective tissues
e.g submucosa of intestine
abundant ground substance
some collagen and elastin fibres (movement)
many cell types
reticular fibrocollagneous tissues
organs with high cellularity e.g liver
reticulum fibres (collagen type III) form a fine network around epithelial or endothelial cells
what is cartillage
specilaised connective tissue
3 types in body
all produce different ECM conponents based on different functions they are expected to perform
all cartillage fromed from:
chondroblasts (progenitor)
mature into chondrocytes
Hyaline cartillage
found in synovial joints
lines ends of bones, nose, ribs
smooth surface to allow articulation
must withstand high compressive forces
type II collagen- less fiborous
what enables hyaline cartilage to withstand high compressive forces put on joints
huge proportion of porteoglycans -aggrecan
5-10% of tissue
draw water into tissue
lubrication and resitance to compression
