Week 2: Autonomic Nervous System- Neurotransmitters Flashcards

1
Q

Cholinergic

A

Bind with ACh

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2
Q

Adrenergic

A

Bind with norepinephrine or epinephrine

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3
Q

Autonomic neurons secrete

A
  • ACh
  • Norepinephrine
  • Epinephrine
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4
Q

All presynaptic ANS neurons are what kind of neuron?

A

Cholinergic

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5
Q

Which postsynaptic ANS neurons are cholinergic?

A

Parasympathetic

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6
Q

Which postsynaptic ANS neurons are adrenergic?

A

Sympathetic

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7
Q

Kinds of cholinergic neurons/receptors

A
  • Muscarinic

- Nicotinic

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8
Q

Muscarinic

A
  • When ACh binds, it initiates G-protein-mediated responses
  • Excitatory or inhibitory
  • Regulates glands, smooth muscle, HR
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9
Q

Nicotinic

A
  • ACh binding leads to fast induction of excitatory postsynaptic potential
  • Nicotine binding = increased task performance and attention
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10
Q

Most common sympathetic postganglionic neurotransmitter

A

Norepinephrine

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11
Q

Where is norepinephrine released?

A

From adrenal medulla

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12
Q

Kinds of adrenergic receptors

A
  • Alpha (subtype 1 and 2)

- Beta (subtype 1 and 2)

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13
Q

Where are adrenergic receptors most abundant?

A
  • Peripheral smooth muscle
  • Cardiac muscle
  • Bronchial smooth muscle
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14
Q

What adrenergic receptors are found in the heart?

A
  • Beta-1

- Increases HR and contractility

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15
Q

What adrenergic receptors are found in the bronchial smooth muscle?

A
  • Beta-2

- Bronchial tree dilation

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16
Q

What adrenergic receptors are found in the skeletal muscle arteriole walls?

A
  • Alpha

- Vasocontriction

17
Q

Alpha blockers

A
  • Block NE binding in blood vessels

- Leads to vasodilation –> decreased BP

18
Q

Beta-1 blockers

A

Decrease HR/contractility

19
Q

Beta-2 agonists

A

Prevent airway constriction in asthma and COPD

20
Q

Primary role of sympathetic NS

A

Maintain optimal blood supply to the organs

21
Q

How does the sympathetic NS maintain blood supply?

A
  • Pupil dilation
  • Bronchodilation
  • Cardiac acceleration
  • Digestion inhibited
  • Piloerection
  • Glucose released
  • Systemic vasoconstriction
22
Q

By-product of epinephrine in the body

A
  • Increased metabolic rate –> increased heat

- Sweating and cutaneous blood flow

23
Q

Primary function of parasympathetic nervous system

A

Energy conservation and storage

24
Q

Nerve for pupillary constriction

A

CN III

25
Q

Nerve for bronchoconstriction

A

CN X

26
Q

Nerve for decreased HR

A

CN X

27
Q

Nerve for salivation

A

CN VII and IX

28
Q

Nerve for lacrimation

A

CN VII

29
Q

Sacral efferents

A
  • Bowel and bladder emptying

- Penile/clitoral erection