Week 2: Autonomic Nervous System- Neurotransmitters Flashcards
Cholinergic
Bind with ACh
Adrenergic
Bind with norepinephrine or epinephrine
Autonomic neurons secrete
- ACh
- Norepinephrine
- Epinephrine
All presynaptic ANS neurons are what kind of neuron?
Cholinergic
Which postsynaptic ANS neurons are cholinergic?
Parasympathetic
Which postsynaptic ANS neurons are adrenergic?
Sympathetic
Kinds of cholinergic neurons/receptors
- Muscarinic
- Nicotinic
Muscarinic
- When ACh binds, it initiates G-protein-mediated responses
- Excitatory or inhibitory
- Regulates glands, smooth muscle, HR
Nicotinic
- ACh binding leads to fast induction of excitatory postsynaptic potential
- Nicotine binding = increased task performance and attention
Most common sympathetic postganglionic neurotransmitter
Norepinephrine
Where is norepinephrine released?
From adrenal medulla
Kinds of adrenergic receptors
- Alpha (subtype 1 and 2)
- Beta (subtype 1 and 2)
Where are adrenergic receptors most abundant?
- Peripheral smooth muscle
- Cardiac muscle
- Bronchial smooth muscle
What adrenergic receptors are found in the heart?
- Beta-1
- Increases HR and contractility
What adrenergic receptors are found in the bronchial smooth muscle?
- Beta-2
- Bronchial tree dilation