Week 1: Pathways- Spinothalamic Flashcards
What’s another name for the spinothalamic tract?
Anterolateral pathway
What information does the spinothalamic tract process?
- Coarse/crude touch
- Temperature
- Discriminative pain
Where does decussation occur in the spinothalamic tract?
At the level of the neuron where the stimulus occurs
What kind of axons transmit coarse/crude touch?
Unmyelinated C fiber axons
Where does crude/coarse touch project?
Left insula
What kind of sensation is crude/coarse touch?
- Less localized
- Pleasurable touch/skin-to-skin
- Tickle/itch
What kind of nerves detect temperature?
- Specialized free nerve endings
- Small myelinated and unmyelinated neurons
What fibers specifically carry cooling info?
A-delta fibers
What fibers specifically carry heating info?
C fibers
What is pain?
- Sensation that triggers autonomic psychological, and somatic motor responses
- Composed of both perceptual and emotional experiences
What does pain sensation interpret stimuli as?
Stimuli is interpreted as indicating current or impending tissue damage
Components of pain
- Fast pain
- Slow pain
Fast pain
- Spinothalamic
- Rapidly conducted by large-diameter myelinated axons
Slow pain
- Spinolimbic
- Slowly conducted by smaller, less heavily myelinated axons
1st order neuron for fast, localized pain
- Small, myelinated A-delta fiber
- DRG ➙ dorsal horn
2nd order neuron for fast, localized pain
Crosses midline immediately and ascends from spinal cord to VPL of thalamus within spinothalamic tract
3rd order neuron for fast localized pain
Thalamus ➙ primary & secondary sensory cortex
Which nerve transmit pain info for the face?
Trigeminal nerve
1st order neuron for face pain
Fibers enter pons and travel down to trigeminal nerve nucleus in medulla/upper cervical region
2nd order neuron for face pain
- Medulla –> thalamus
- Crosses midline to ascend back up to VPM nucleus of thalamus
3rd order neuron for face pain
Thalamus to cerebral cortex
Crossed analgesia
- Ipsilateral analgesia in the face
- Contralateral analgesia in the body