Week 1: Neurotransmitters Flashcards

1
Q

Types of neurotransmitters

A
  • Fast-acting

- Slow-acting

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2
Q

Fast-acting neurotransmitter

A
  • Act directly

- Transmission requires less than 1/1000 of a second

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3
Q

Slow-acting neurotransmitter

A
  • Act indirectly

- Transmission requires 1/10 s to minutes

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4
Q

Neuromodulators

A

Alter neural function by acting at a distance away from the synaptic cleft

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5
Q

How long does it take for neuromodulators to act?

A

More slowly and last longer than neurotransmitters

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6
Q

How long do the effects of neuromodulators last?

A

Minutes to days

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7
Q

Effect of Ach in skeletal muscle

A

Muscle contraction

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8
Q

Effect of Ach in ANS

A
  • Slow heart
  • Constrict pupil
  • Increase GI secretion/contraction
  • Parasympathetic
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9
Q

Effect of Ach in the brain

A
  • Arousal
  • Pleasure
  • Reward
  • Cognitive function
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10
Q

Effect of glutamate in the brain

A
  • Excitatory effect

- Learning and memory

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11
Q

Effect of glycine in the spinal cord

A

Inhibition

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12
Q

Effect of GABA in the CNS

A
  • Inhibition
  • Sedation
  • Anti-anxiety
  • Anti-seizure
  • Sleep inducing
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13
Q

Effect of dopamine on the emotional system?

A

Feeling of wanting a reward

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14
Q

Effect of dopamine on the basal ganglia?

A
  • Control of movement
  • Attention
  • Decision making
  • Goal-directed behavior
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15
Q

Effect of dopamine on the frontal lobe?

A

Thinking, planning

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16
Q

Effect of norepinephrine on the adrenal gland, sympathetic NS?

A
  • Increased HR and force
  • Dilation of bronchioles
  • Inhibition of peristalsis
17
Q

Effect of norepinephrine on the emotional system, some cerebral cortex?

A
  • Control of mood

- Increased attention to sensry

18
Q

Effect of serotonin on the CNS?

A

Regulates sleep, appetite, arousal, and mood

19
Q

Effect of histamine on the brain?

A

Regulates wakefulness and attention

20
Q

Endogenous opioid peptides produced?

A

Inhibit nociceptive signals

21
Q

Substance P

A
  • Signals tissue damage

- Involves perception of normally innocuous stimuli as painful

22
Q

Calcitonin gene-related peptide

A

Long-term neural changes in migraine HAs

23
Q

Which neurotransmitters are amino acids?

A

Glycine, glutamate, and GABA

24
Q

Which neurotransmitters are amines?

A

Domaine, norepinephrine, serotonin, and histamine

25
Q

Which neurotransmitters are peptides?

A

Opioids, substance P, clacitonin gene-related peptide