Week 13: Stimulants & Nonstimulants Flashcards
ADHD most commonly used agents
stimulants (increasing dopamine and norepinephrine)
what do you monitor in stimulants? especially each visit?
decreased appetite
difficulty sleeping
tics (sudden, repetitive, involuntary movements or sounds)
personality changes (anxiety, irritability)
stomach aches
h/a
each visit: BP, height/weight, HR
FDA warning on methylphenidate (Ritalin)
complications if pt has tics, glaucoma, HTN, seizures, MAOIs, mental health conditions
FDA warning on amphetamines (Adderall) can cause complications if pt has
heart dz, HTN, hyperthyroidism, glaucoma, drug misuse, mental health condition, tics, liver/kid problems, thyroid problems, seizures
non-stimulant med that is approved by FDA to tx ADHD
- strattera (atomoxetine)
- clonidine, guanifacine
endocannabinoid system responsible for ?
what receptors
relaxing, eating, sleeping, and forgetting
CB1: in CNS; modulate cognition, memory, motor function, analgesia
CB2: in tissues; immune function (WBC, bone marrow, tonsils, thymus, spleen)
THC
psychoactive
- enhances analgesia
- anti-inflammatory effects
- nausea/vomiting
- more CNS effects
CBD
non psychoactive
-analgesic, anti-inflammatory, anti-seizure
no CNS side effects
sativa
uplifting
energetic
anti-depressive
daytime use
indica
relaxing, calming, sedating
night time use
CBD/THC
combo mitigates psychoactiv THC
day or night
cannabis side effects
Xerostomia, nausea, and vomiting often with excessive use, drowsiness, somnolence, vertigo/dizziness
Cannabinoid hyperemesis syndrome
occur in ppl who smoke excess marijuana long term