Week 13: SNRI Flashcards
1
Q
SNRI MOA
A
boosts serotonin, norepinephrine, dopamine (for major depression) in prefrontal cortex
2
Q
which SNRI’s are bad for hypertensive pt’s or require monitoring of blood pressure and HR? (they are dose dependent)
A
venalfaxine and desvenlafaxine
3
Q
duloxetine (cymbalta) c/c
A
may inc concentrations of antipsychotics (need decreased dosages)
4
Q
fetzima need dose adjustments in
A
SNRI
-for renal impairment, elderly
5
Q
is ssri or snri better for depression AND pain?
A
SNRI more effective
-SNRI & TCA (both work on serotonin and norepinephrine reuptake) relieves pain with fibromyalgia, low back pain, postherpetic neuralgia, and diabetic peripheral neuropathy
6
Q
to avoid discontinuation syndrome, need to
A
tape off slowly
