Week 13: Mood Stabilizers

Question 1

long term tx for bipolar disorder meds

Answer 1

lithium, carbamazepine, valproic acid

Question 2

most safe antidepressant and mood stabilizing med for pregnancy

Answer 2

lamotrigine (lamictal)

Question 3

lithium indication

Answer 3

manic, maintenance for manic depressive pts, off label for MDD and bipolar, decrease suicide ideation

Question 4

mood stabilizer meds

Answer 4

lithium, depakote, lamictal, carbamazepine

Question 5

valproate/depakote need what tests

Answer 5

for acute mania

LFTs and platelets few times a year
coagulation tests before surgery

monitor for metabolic syndrome

Question 6

lamotrigine/lamictal need what testing?

Answer 6

for bipolar I

NONE!
bind to melanin tissues so opthalmological checks considered

ONLY mood stabilizer for pregnancy

Question 7

carbamazepine (tegretol) for what and testing needed?

Answer 7

bipolar and maintenance, psychosis, schizophrenia

tests before starting: cbc, lft, kidney, TSH
during: cbc q 2-4 weeks x 2 months, then every 3-6 months, LFT, kidney, TSH every 6-12 months

Question 8

carbamazepine need what screening

Answer 8

HLA-B 1502 allele in asians bc risk of steven jonson syndrome