week 12 - spleen Flashcards
spleen is part of the ____ system
reticuloendothelial
spleen is a intraperitoneal organ in the ___
LUQ / left hypochondrium
t/f: spleen is essential to life
false - it is NOT essential
Responsible for the phagocytosis of damaged/old cells, foreign material and pathogens
spleen
Active in ___ during the first part of fetal life
hematopoiesis
spleen is composed primarily of ___ tissue
lymph
spleen is ____ to the body and fundus of the stomach and pancreatic tail
posterolateral
spleen is ___ to the left colic gutter
posterior
left kidney is ___ to the medial section of spleen
posteroinferior / inferomedial
diaphragm, lung, pleura, and ribs are ___ to spleen
posterior
only portion of spleen not covered by peritoneum
splenic hilum
what protects the spleen
ribs
spleen is lateral to
stomach and lesser sac
longest dimension of spleen should not exceed
13cm
___ structure with ___ superior surface and ___ inferior surface
ovoid
convex
concave
describe the contour of the spleen
smooth
why do we look at the spleen
evaluate shape
t/f: spleen is highly vascularized
true
spleen is covered in ___ except for the ___
peritoneum
hilum
spleen is composed of __ and ___ pulp
white
red
Lymphatic tissue that surrounds and follows the smaller splenic arteries,
Consists of the Malpighian corpuscles
white pulp
Small nodular masses of lymphoid tissue attached to smaller arterial branches
Malpighian corpuscles
Lymphoid tissue follicles surround ___ and are scattered throughout the ___
arteries
spleen
Red pulp is ___ vascular than white pulp
more
Contains large numbers of RBCs
red pulp
red pulp surround ___
venous sinuses
red pulp consists of
splenic sinuses and cords
capillaries are ___ thus, RBC __ enter the venous sinuses
permeable
can
vascular supply to spleen
splenic artery from celiac trunk
splenic artery courses ___ towards the spleen
laterally
___ and ___ branches arise from the splenic artery
pancreatic and gastric
splenic artery at hilum branches into ___ arteries
2-4 lobar
lobar arteries branch into ___ then into ___ that terminate in ___
lobular
splenic arteries
capillaries
helps with the filtering function of the spleen
capillaries
The capillaries in spleen anastomose with tiny venous sinuses that form splenic ___
venules
converge to form the splenic vein
venules
splenic vein course medially to the confluence with ___ to form the ___
superior mesenteric vein (SMV/IMV)
portal vein
Nerves to the spleen accompany the ____ artery and are derived from the ____
splenic
celiac plexus
lymph vessels emerge from ___ and pass through other lymph nodes along the ___ artery then drain into the ____ nodes
splenic hilum
splenic
celiac
spleen acts as reservoir for
blood
4 major function of spleen
- defense
- hematopoiesis (produce RBC & WBC)
- RBC and platelet destruction
- blood reservoir
spleen produces (6)
lymphocytes phagocytes plasma cells antibodies RBC WBC
spleen stores ___ and ___
iron
metabolites
spleen regulates the life span of
platelets and leukocytes
type of cell destroys invading microbes
platelet
what type of cells in spleen are directly involved in immune response
memory cells
__ pulp produces lymphocytes and monocytes for ingestion and digestion of pathogens
white
when is the spleen involved in hematopoiesis
- in developing fetus
- in adult suffering severe hemolytic anemia
what is hematopoiesis
production of RBC and WBC
what is culling
removal of abnormal RBC