week 12 Flashcards
secret pepsinogen an inactive enzyme
chief cells
secrete hydroochloric acid, which activated the pepsinogen
parietal cells
secrete cmucous to protect the stomach walls
mucous cells
What does parietal cells do
stimulate by acetylcholine from the cholinergic nerve fibers
stimulated by gasterin and histamin
activates the pepsinogen and pepsin
creates the right pH fro protein digestion
What cause GERD (Gastroesophageal Reflux)
Weakened lower esophageal sphincter delayed gastric emptying hiatal hernia obesity overeating acid overproduction
Acid secretion is increased by
carbonated beverages, smoking, alcohol, coffee, spicy foods
what is tissue erosion of the esophagus called
barretts esophagus
antacids
aluminum hydroxide (amphogel)
coating agents
sucralfate (carafate)
histamine 2(h2) receptor antagonists
cimetidine (tagamet)
proton pump inhibitors
omeprazole (prilosec)
what does antacids aluminum hydroxide (amphogel) do to the body and what is it used for
neutralize gastric acidity and decrease rate of gastric emptying
to decrease the amount of acid in the stomach
what are the adverse reactions of antacids aluminum hydroxide (amphogel)
aluminum cause constipation,
magnesium-diarrhea
calcium- constipation
if to much is taken shift in blood acid base resulting in alkalosis
if contain carbonate (alka-seltzer)-gas abdominal distention
what do coating agents sulfate (carafate) do to the body and what is it used for
form a complex that adheres to the crater of the ulcer, protecting it from acid, bile, and pepsin
to treat duodenal ulcers
what are the adverse reactions of coating agents sulfate (carafate)
N/D constiaption gastric discomfort