week 12 Flashcards

1
Q

secret pepsinogen an inactive enzyme

A

chief cells

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2
Q

secrete hydroochloric acid, which activated the pepsinogen

A

parietal cells

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3
Q

secrete cmucous to protect the stomach walls

A

mucous cells

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4
Q

What does parietal cells do

A

stimulate by acetylcholine from the cholinergic nerve fibers
stimulated by gasterin and histamin
activates the pepsinogen and pepsin
creates the right pH fro protein digestion

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5
Q

What cause GERD (Gastroesophageal Reflux)

A
Weakened lower esophageal sphincter
delayed gastric emptying
hiatal hernia
obesity
overeating
acid overproduction
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6
Q

Acid secretion is increased by

A

carbonated beverages, smoking, alcohol, coffee, spicy foods

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7
Q

what is tissue erosion of the esophagus called

A

barretts esophagus

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8
Q

antacids

A

aluminum hydroxide (amphogel)

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9
Q

coating agents

A

sucralfate (carafate)

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10
Q

histamine 2(h2) receptor antagonists

A

cimetidine (tagamet)

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11
Q

proton pump inhibitors

A

omeprazole (prilosec)

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12
Q

what does antacids aluminum hydroxide (amphogel) do to the body and what is it used for

A

neutralize gastric acidity and decrease rate of gastric emptying

to decrease the amount of acid in the stomach

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13
Q

what are the adverse reactions of antacids aluminum hydroxide (amphogel)

A

aluminum cause constipation,
magnesium-diarrhea
calcium- constipation
if to much is taken shift in blood acid base resulting in alkalosis
if contain carbonate (alka-seltzer)-gas abdominal distention

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14
Q

what do coating agents sulfate (carafate) do to the body and what is it used for

A

form a complex that adheres to the crater of the ulcer, protecting it from acid, bile, and pepsin

to treat duodenal ulcers

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15
Q

what are the adverse reactions of coating agents sulfate (carafate)

A

N/D constiaption gastric discomfort

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16
Q

HIstamine H2 blocker are used for what

A

short term treatment of gatric of duodenal ulcers

maintancence for duodenal ulcer of GERD

17
Q

What are the side effects of histamine H2 blocker

A

confusoin, headache, and diarrhea

18
Q

what does proton pump inhibitors Omeprazole (prilosec) do to the body and what is it used for

A

bind irreversibly to gastric proton pump, prevent relese of gastric acid

used to treat of GERD, PUD, and erosive gastritis

19
Q

What does gastrointestinal stimulant metroclopramids HCL (reglan) do to the body and what is it used for

A

stimulates gastric emptying by ^ peristalsis

management of diabetes gastro paresis
symtomatic treatment of GERD