Weakness Colloquium

Question 1

Why do MS patients get urinary symptoms?

Answer 1

Miscommunication between the detruser muscle and the bladder sphincter due to spinal cord lesions

Question 2

What is the different between papilloedema and papillitis?

Answer 2

Both are disc swelling

• Papilloedema is due specifically to raised ICP (usually bilateral)
• Papilloedema is due to inflammation only (usually unilateral)

Question 3

What are some the top two differentials in a young female with subacute sensory disturbance and LL weakness?

Answer 3

Spinal cord myelitis

GBS

Question 4

What is transverse myelitis?

Answer 4

Inflammation demyelination that functionally transects the spinal cord

Question 5

What pattern of sensory loss do you get in peripheral neuropathies?

Answer 5

Glove and stocking

Dermatomal

Mononeuropathy

Question 6

What is Uhthoff’s phenomenon?

Answer 6

Demyelinating pathologies are worse with heat

Question 7

What is a pyramidal pattern of weakness in the LL like?

Answer 7

Predominantly flexion weakness

Question 8

Why does L’Hermitte’s sign occur?

Answer 8

Stretching of the dorsal column in the cervical spine causes sensory changes