WBC Parameters Flashcards
Leucocytosis - Increased WBCs
Neutrophilia
Lymphocytosis
Monocytosis
Eosinophilia
Basophilia
Leukopenia - Decreased WBCs
Neutropenia
Lymphopenia
Monocytopenia
Eosinopenia
Steps for cells to leave blood vessels
Marginalisation
Adhesion
Migration
Causes of neutrophils
Epinephrine - fight or flight
Glucocorticoids
Infection
Stress - cortisol
Chronic neutrophil leukemia
Left Shift
More immature cells than mature cells present due to acute infection
Regenerative
Segmented>immature
Neutrophils ↑
Degenerative
More Immature than segmented
Bone marrow is producing neutrophils but they are disappearing into tissues quickly
Neutrophils ↔ ↓ or (↑)
Right shift is the opposite -caused by cushing’s
Neutropenia Causes
Inflammation - overwhelming infections
Decreased production - neoplasia, toxicity
Interpretation of neutropenia in acute inflammation
Dog or Cat
Very severe lesion
Horse
Probable severe lesion
Cow
Neutropenia typical in inflammation regardless of severity
Cytopenia
Reduce cells in general
When there is bone marrow disruption