Neoplasia Terminology

Question 1

Cancer

Answer 1

Malignant neoplasia

Question 2

Neoplasia

Answer 2

Abnormal and uncontrolled cell proliferation

Question 3

Malignant

Answer 3

Invades locally and spread by metastasis (distant from primary tumour)

Question 4

Tumour/Neoplasm

Answer 4

Abnormal mass of tissue as a result of neoplasia

Question 5

Mutagenesis

Answer 5

Introduction of irreversible genetic change to cells by a mutagenic initiation agent

Question 6

Oncogenesis

Answer 6

Process of healthy cells becoming cancer cells

Question 7

Benign

Answer 7

Won’t invade locally or spread to new anatomic location
Usually harmless
Not cancerous

Question 8

Metastases

Answer 8

Spread of tumour to a new anatomical location away from primary tumour

Question 9

Adenoma

Answer 9

Benign tumour of epithelial tissue

Question 10

Carcinoma

Answer 10

Malignant tumour of epithelial origin

Question 11

Sarcoma

Answer 11

Malignant tumour of bone or soft tissue origin

Question 12

Lipoma

Answer 12

Benign fatty tumour

Question 13

Thymoma

Answer 13

Malignant tumour of thymus origin
AKA Thymic Epithelial Tumour (TET)

Question 14

Myeloma

Answer 14

Malignant tumour of bone marrow origin

Question 15

Lymphoma

Answer 15

Malignant tumour of lymphatic origin

Question 16

Proto-oncogene

Answer 16

Unmutated genes which are involved in growth factor pathways
Allow a cell to proliferate

Question 17

Oncogene

Answer 17

Mutated gene
Promotes autonomous growth
○ Uncontrolled proliferation
Codes for specific oncoproteins

Question 18

Oncoprotein