WBC Flashcards

1
Q

outline the innate immune cells

A

macrophage
granulocytes
dendritic cells
NK cells

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2
Q

what are the granulocytesq

A

neutrophils
eosinophils
basophils
mast cells

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3
Q

innate immunity

A
fast, non-sepecific, genertic
body surfaces
phagocytosis
antimicrobial substances
inflmation
immunlogical surelance
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4
Q

adaptive immunity

A

antiegn specific
highly specalised
-B cells, T cells
leads to memory

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5
Q

lymphocytes

A

central role in immune system protecting against viral ifections

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6
Q

subdivisions of lymphocytes

A

Nk cells
B cells
T cells

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7
Q

B cell CD markers

A

CD19

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8
Q

T cell CD markers helper

A

CD4

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9
Q

T cell cytotoxic CD markers

A

CD8

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10
Q

role of B lymphocytes

A

made in bone marrow
circulate in blood
mount antigen specific immune response with antibodies
- can neutralise and activate complement

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11
Q

plasma cels

A

prduce and secrete antigen specific antibodies

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12
Q

name of immature T cells

A

thymocytes

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13
Q

function of thymus

A

generate and select T cells

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14
Q

where does positive selection occur

A

cortext

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15
Q

where does neg selection occur

A

cortext medulla border

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16
Q

where to T cells undergo diffentiation

A

medulla

17
Q

cytotoxic T lymphocytes

A

recognise and eliminate inefcted cells
CD8
use MCH class 1

18
Q

how do cytotoxic T cells kill infected cells

A

secrete IFN to limit viral replicatoin

apoptosis of the cell

19
Q

T helper cells

A

help other imune cells become fully functional
CD4
MCH calss 2

20
Q

polymorphonuclear WBCs

A

granulocutes
neutrophils
eosinophils
basophils

21
Q

monoculear WBC

A

lymphocytes

monocytes

22
Q

what is granulocotye nomenclature based on

A

romanoswsy staining

23
Q

what colour o neutrophols stain?

A

neutral

24
Q

what colour do eosinophils stain

A

orange

25
Q

function of neutrophils

A

location chemotaxis

phagocytosis

26
Q

role of the respiratory burst

A

before phagocyotisis

increases O2, glycolysis, more MPO activity

27
Q

defects of icrobial killing

A

MPO deficiency
failure of respiraotry burst
inherited defects in neurotphil migration