wauson-herbal Flashcards
Echinacea tx
inflammation, common cold, influenza
Garlic tx
Hypertension
Ginkgo tx
cognitive decline
Ginseng tx
common cold, boost immune system, mental and physical performances, lower BP and glucose
Milk thistle
Liver disease in general! liver disease, cirrhosis, hepatitis, reduce heaptotoxicity
St. John’s worts
depression
Saw Palmetto
Benign Prostatic hyperplasia
Butterbur
migrane
feverfew
migrane
Coenzyme Q10
statin induced myopathy, migranes, hypertension
Glucosamine and chondroitin
osteoarthritis
Melatonin
insonmia
which supplements increase immune system function
Echinacea, ginseng
which ones have the adverse of effects of bleeding?
Ginkgo, Garlic, ginseng, Glucosamine and chondroitin, feverfew, CoQ10
decrease reproductive system adverse effect
Melatonin
Induce hypoglycemia adverse effect
Ginseng
Mechanism of Echinacea
- E. purpurea increases WBCs, monocytes, neutrophils, and natural killer cells. Also shown to increase the production of interleukins and TNF alpha.
- E.purpurea shown to inhibit cyclooxygenases –>antiinflmmatory effect
Mechanism of garlic
- Inhibits ACE (decreased vasoconstriction)
- Decrease in proliferation and migration of VSMC decrease in wall/lumen ratio decreased vasoconstriction
- Increase in NO bioavailability reduction of oxidative stress enhanced vasodilation
- Increase in H2S production enhanced vasodilation
mechanism of Saw Palmetto
- Active agents may be sterols and fatty acids: inhibit 5 alpha reductase conversion of testosterone into dihydrotestosterone (DHT) in vitro
st john’s worts mechanism
inhibits reuptake of serotonin, dopamine, and NE
which two drugs are the most important drugs for decreasing concentraton serum?
St Johns Worts and garlic
which supplement decrease serum drug by inducing p450
St john worts
which decrease bioavailability of drugs by inducing p-glycoprotein transporter
garlic, st johns worts
