antibacterial tx

Question 1

uncomplicated skin and soft tissue

Answer 1

penecillin, cephalexin

Question 2

uncomplicated skin and soft tissue if allergy to penecillin

Answer 2

vancomycin or clindamyacin

Question 3

complicated skin and soft tissue/and what to replace if allergy

Answer 3

penecillin + lactamse inhibitor (Ticarcillin + clavulanate);

allergy, use imipenem

Question 4

MRSA

Answer 4

vancomycin, Linezolid, daptomycin

Question 5

osteomyelitis

Answer 5

vancomycin, ceftriazone or cefepime

Question 6

orthopedic surgery infection

Answer 6

penecillin + lactamase inhibitor (ticarcillin/clavulanate)

Question 7

Empiric/Mrsa Septic arthritis

Answer 7

Empiric: ceftriaxone (3rd gen)

MRSA: vancomycin, linezolid, daptomycin

Question 8

prosthetic joint

Answer 8

rifampin

Question 9

acute sinusitis

Answer 9

Amoxocillin + clavulanate (not required as combo)

Question 10

chronic bronchitis

Answer 10

Amoxocillin + clavulanate (not required as combo)

Question 11

pharyngitis/ allergy replacements?

Answer 11

penecillin or amoxicillin

alternative: cephalosporin

Serious allergy: clindamycin, clarithromycin, azithromycin

Question 12

Ambulatory community acquired bacteria pneumonia

Answer 12

macrolides: erythromycin, azithromycin, clarithromycin

Question 13

Hospitalization community acquired bacteria pneumonia

Answer 13

beta lactam + macrolide

Question 14

MRSA community acquired bacteria pneumonia

Answer 14

vancomycin, linezolid

Question 15

cystitis

Answer 15

trimethoprim/sulfamethoxazole (TMP-SMX)

Question 16

Pyelonephritis

Answer 16

TMP-SMX

Question 17

uncomplicated UTI with kidney infection

Answer 17

Fluoroquinolone (Ciprofloxacin)

Question 18

complicated UTI

Answer 18

fluoroquinolone, TMP-SMX

Question 19

Prostatitis

Answer 19

Fluoroquinolone, TMP-SMX

Question 20

intra-abdominal infections

Answer 20

Ticarcillin + clavulanate

Question 21

C diff infection: moderate/severe

Answer 21

Moderate: metronidazole
Severe: vancomycin

Question 22

community acquired bacteria meningitis >2months

Answer 22

ceftriaxone or cefotaxime + vancomycin

Question 23

neonatal meningitis <2months

Answer 23

Ampicilin + cephalosporin +/- gentamicin

Question 24

Sepsis syndrome

Answer 24

3rd/4th cephalosporin + vancomyin

ie. cefepime _vacomycin

Question 25

Endocarditis

Answer 25

Ceftriaxone + vancomycin

Question 26

fever and neutropenia

Answer 26

ciprofloxacin+ amoxicillin/clavulanate

Question 27

ESBL (gram neg resistant bacteria multi resistant)

Answer 27

Imipenem or meropenem (carbapenem)

Question 28

Carbapenemases Multidrug resistant:

Answer 28

polymyxin B, Tigecycline

Question 29

What are the main strains that enteroccus is resistant to?

Answer 29

ampicillin, gentamicin, streptomycin, vancomycin

Question 30

Enterococci Multi-drug resistant tx:

Answer 30

Linezolid, Daptomycin, Tigecycline (replace Vancomycin since enteroccus is resistant to it)

Question 31

what treats rocky mountain spotted fever

Answer 31

chloramphenicol

Question 32

what treats plague

Answer 32

beta lactam + aminoglycoside