antibacterial tx Flashcards

1
Q

uncomplicated skin and soft tissue

A

penecillin, cephalexin

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2
Q

uncomplicated skin and soft tissue if allergy to penecillin

A

vancomycin or clindamyacin

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3
Q

complicated skin and soft tissue/and what to replace if allergy

A

penecillin + lactamse inhibitor (Ticarcillin + clavulanate);

allergy, use imipenem

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4
Q

MRSA

A

vancomycin, Linezolid, daptomycin

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5
Q

osteomyelitis

A

vancomycin, ceftriazone or cefepime

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6
Q

orthopedic surgery infection

A

penecillin + lactamase inhibitor (ticarcillin/clavulanate)

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7
Q

Empiric/Mrsa Septic arthritis

A

Empiric: ceftriaxone (3rd gen)

MRSA: vancomycin, linezolid, daptomycin

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8
Q

prosthetic joint

A

rifampin

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9
Q

acute sinusitis

A

Amoxocillin + clavulanate (not required as combo)

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10
Q

chronic bronchitis

A

Amoxocillin + clavulanate (not required as combo)

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11
Q

pharyngitis/ allergy replacements?

A

penecillin or amoxicillin

alternative: cephalosporin

Serious allergy: clindamycin, clarithromycin, azithromycin

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12
Q

Ambulatory community acquired bacteria pneumonia

A

macrolides: erythromycin, azithromycin, clarithromycin

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13
Q

Hospitalization community acquired bacteria pneumonia

A

beta lactam + macrolide

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14
Q

MRSA community acquired bacteria pneumonia

A

vancomycin, linezolid

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15
Q

cystitis

A

trimethoprim/sulfamethoxazole (TMP-SMX)

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16
Q

Pyelonephritis

A

TMP-SMX

17
Q

uncomplicated UTI with kidney infection

A

Fluoroquinolone (Ciprofloxacin)

18
Q

complicated UTI

A

fluoroquinolone, TMP-SMX

19
Q

Prostatitis

A

Fluoroquinolone, TMP-SMX

20
Q

intra-abdominal infections

A

Ticarcillin + clavulanate

21
Q

C diff infection: moderate/severe

A

Moderate: metronidazole
Severe: vancomycin

22
Q

community acquired bacteria meningitis >2months

A

ceftriaxone or cefotaxime + vancomycin

23
Q

neonatal meningitis <2months

A

Ampicilin + cephalosporin +/- gentamicin

24
Q

Sepsis syndrome

A

3rd/4th cephalosporin + vancomyin

ie. cefepime _vacomycin

25
Q

Endocarditis

A

Ceftriaxone + vancomycin

26
Q

fever and neutropenia

A

ciprofloxacin+ amoxicillin/clavulanate

27
Q

ESBL (gram neg resistant bacteria multi resistant)

A

Imipenem or meropenem (carbapenem)

28
Q

Carbapenemases Multidrug resistant:

A

polymyxin B, Tigecycline

29
Q

What are the main strains that enteroccus is resistant to?

A

ampicillin, gentamicin, streptomycin, vancomycin

30
Q

Enterococci Multi-drug resistant tx:

A

Linezolid, Daptomycin, Tigecycline (replace Vancomycin since enteroccus is resistant to it)

31
Q

what treats rocky mountain spotted fever

A

chloramphenicol

32
Q

what treats plague

A

beta lactam + aminoglycoside