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pharm exam 4 > antimalarial > Flashcards

antimalarial Flashcards

1
Q

which drug is effective in eliminating all stages of ALL species of Plasmodium? which drug is most?

A

Chloroquine**, quinine , Mefloquine, doxycycline, Artemisinin

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2
Q

which drug interferes with hemoglobin degradation

A

Quinine

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3
Q

which drug has the poorest therapeutic:toxic ratio of all antimalarial drugs?

A

Quinine

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4
Q

which drug can cause psychiatric dreams

A

Mefloquinone

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5
Q

Primaquine side effects

A

RBC lysisw/ peopler with G6PD deficiency can cause hemolytic anemia

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6
Q

1st line drug to use during travelling abroad

A

Malarone: Atovaquone + Proguanil

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7
Q

Cinchonism side effect

A

Quinine

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8
Q

which drug will cause hemolytic anemia

A

pramaquine

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9
Q

which drug cannot be used as prophylaxis? reason?

A

Quinine due to its high toxicity

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10
Q

which drug requires screening for G6PD deficiency before administering?

A

primaquine

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11
Q

which drug is highly efficacious for treating P. Falciparum malaria

A

Malarone

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12
Q

what makes up Malarone

A

Atovaquone + proguanil

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13
Q

which drug is primarily prophylaxis

A

Doxycycline

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14
Q

DRUG of choice to tx dormant liver (hypnozoite) form of P vivax and Povale

A

Primaquine

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15
Q

which antimalarial drug is a protein synthesis inhibitor

A

Doxycycline

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16
Q

which drug should be avoided for children and pregnancy?

A

Doxycycline

17
Q

which anti-malarial drug is the “chinese wood worm”?

A

Artemisinin Deriv: Iumefantrine

18
Q

which drug increases sensitivity to sunburn

A

doxycycline

19
Q

what are all the drugs for antimalaria

A

chloroquine, quinine, mefloquine, primaquine, Malarone, doxycycline, Artemisinin deriv

20
Q

what plasmodium are prone to hyponozoite form in liver?

A

Pvivax and Povale

21
Q

which plasmodium is chloroquine resistant to

A

P falciparum

22
Q

which drug is Malarone highly effiacious to?

A

P falciparum malaria

pharm exam 4 (13 decks)

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