warp Flashcards

1
Q

what antidepressants cause migraine and headaches and collapse

A

MAOi - hypertensive criisis

is this happens crisis use alpha blocker to treat

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2
Q

can’t move eye down and medially can’t look at tip of nose and left eye is slightly deviated upwards , with double vision

A

CN4

trochlear nerve
suppose SO
depression of eyeball

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3
Q

right 3rd nerve palsy

A

right eye down and out

unable to adduct right eye

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4
Q

right 4th palsy

A

right eye turn up and out , right eye elevates too

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5
Q

benzodiapsxpeis work by inhaling GAAB complex

A

enhances cellular entry of CL-
hyper polarises the cell making it harder to simulate

inhibitory stimulus enhanced

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6
Q

long term side of l-dopa avoided by giving ropinirole

A

dyskinesia - involuntary movements

carbidopa - decarboxylase inhibitors 
monoamine oxidase b inhibitors e.g. rasagiline 
OCMT inhibitors - entacapone 
anticholinergics 
amantadine 
dopamine agonists
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7
Q

ropinirole stimulates the post synaptic dopamine receptors D2 in the CNS and PNS
what are some adverse reactions

A

n+v dyspepsia etc

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8
Q

direct pathway

A

cerebral cortex excites via glutamate striatum this then inhibits medial palladium this then inhibits the motor thymus inhbirtn the motor cortex

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9
Q

direct pathway what receptor

A

D1

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10
Q

indrifet pathway what receptor

A

D2

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11
Q

what protein is primary associate with neurofibrillary tangles

A

tau

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12
Q

what enzyme is responsible fro conversion of dopa to dopamine

A

DOPA decarboxylase

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13
Q

what is dopamine prescuor aa

A

tyrosine

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14
Q

most likely CN t risk of posterior communicating artery aneurysm

A

oculomotor nerve

runs close to this artery resulting in third nerve palsy

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15
Q

patient with MS suspect to peripheral nerve damage and no plaques found
what ytmpom would you most likely observe in patient

absent tenone reflex 
babinski 
hypetonic msucles 
muscle wasting 
paralysis of muscle groups
A

absent deep tendon reflexes

LMN

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16
Q

UMN lesion

A
weakness
atrophy absent 
reflexes icnreased
increased tone 
fasiciutlaitons are absent 
bibniski 
LMN opposite. 
weakness till present 
atrophy 
reflex decreased 
decreased tone 
fasciculations 
no babinski
17
Q

how to reverse opiate morphien or heroin overdose

A

naloxone