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Matt's Block 08 - Metabolism > W27-L6: Drugs used in obesity > Flashcards

W27-L6: Drugs used in obesity Flashcards

1
Q

What is Phentermine?

A

Amphetamine derivative that increases NA, DA and 5-HT

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2
Q

Why is phentermine not that useful?

A

Tolerance develops are 3 weeks, so only useful in the short term

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3
Q

What is orlistat?

A

An inhibiter of gastric and pancreatic lipases which decreases dietary fat absorption

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4
Q

How does orlistat work?

A

forms a covalent bond with lipase which means it can no longer hydrolyse triglycerides, decreased fat
absorption and increased
excretion

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Matt's Block 08 - Metabolism (17 decks)

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