von Willebrand disease Flashcards
1
Q
what is von willebrand disease?
A
most common inherited cause of abnormal prolonged bleeding
2
Q
what is the pathophysiology of von willebrand disease?
A
deficiency, absence or malfunctioning of a glycoprotein called von Willebrand factor
3
Q
presentation of von Willebrand disease?
A
bleeding gums, epistaxis, easy bruising, menorrhagia, heaving bleeding with surgery
4
Q
how is vWD diagnosed?
A
history of bleeding, family history, bleeding assessment tools and laboratory investigations.
5
Q
management of vWD?
A
management is in response to significant bleeding or trauma. desmopressin, tranexamic acid, vW factor and factor 7
