Vitamin E Flashcards
What are the 8 Vitamin E compounds?
- 4 tocopherols ( alpha, beta, gamma, delta)
- 4 tocotrienols (alpha, beta, gamma, delta)
They all have varying degrees of bioactivity
The body’s most preferred form is alpha tocopherol
Natural form is more potent that synthetic form
How is Vitamin E absorbed?
Absorbed passively
Amount absorbed depends on how much fat is eaten with it, ranges from 20-70%
How is Vitamin E transported around the body?
- Via micelles into the enterocyte
- Via chylomicrons through the lymphatic system
- Via lipoproteins from the liver to the cells
Where is Vitamin E stored in the body?
90% in adipose tissue
How is Vitamin E excreted from the body?
Urine, bile and skin
What are the functions of Vitamin E?
- Main function is as an antioxidant and preventing the propagation of free radicals
- Alpha tocopherol stabilises peroxyl radicals by donating an electron, and prevent the lipid oxidation chain reaction
What causes Vitamin E deficiency?
- malabsorption
- increased requirements for smokers
- genetic defects of transporters
What are the risks of Vitamin E toxicity?
High doses of vitamin E interfere with the clotting ability of Vitamin K and so causes blood thinning and risk of haemorrhages
What are good sources of Vitamin E?
- Sunflower seeds
- Avocado
- Almonds